Poly (γ-Alkyl-α, l-glutamate)s, derived from long chain paraffinic alcohols

Comblike Complexes of Poly(aspartic acid) and Alkyltrimethylamonium Cationic Surfactants

“…[1][2][3] One distinguished class of these polymer systems is that comprising helical poly(a-peptide)s bearing long linear polymethylene side chains. [2,3] Such type of systems are unique in displaying a combination of properties that includes a high solubility in organic solvents and the ability to generate periodically layered structures at the nanometric scale.…”

“…[1][2][3] One distinguished class of these polymer systems is that comprising helical poly(a-peptide)s bearing long linear polymethylene side chains. [2,3] Such type of systems are unique in displaying a combination of properties that includes a high solubility in organic solvents and the ability to generate periodically layered structures at the nanometric scale. Very recently, similar structures have been shown to occur also in poly(a-alkyl b,L-aspartate)s [4,5] and poly(a-alkyl g-glutamate)s, [6,7] two families of unconventional polypeptides that are able to take up regularly folded conformations of a-helix type.…”

Copoly(γ,dl-glutamate)s containing short and long linear alkyl side chains

“…After the pioneer work of Watanabe describing the layered biphasic structure of poly(g-alkyl a,L-glutamate)s [3], a good number of papers exploring this behavior in other related poly(apeptide)s were published [4,5]. The occurrence of similar structures in comb-like poly(b-peptide)s, specifically poly(a-alkyl b,L-aspartate)s was later reported and these systems have been extensively investigated in these last years [6].…”

Imidazole‐initiated polymerizations of α‐amino acid N‐carboxyanhydrides – simultaneous chain‐growth and step‐growth polymerization

“…Between 1950 and 1975 Polypeptides prepared by homo‐ or copolymerization of α‐amino acid N ‐carboxyanhydrides (NCAs) played an important role as models of biogenic polypeptides and proteins 1–6. More recently, the interest in polypeptides derived from NCAs has again increased either in connection with cholesteric liquid crystalline materials7–9 or in connection with syntheses and applications of biodegradable materials 10–15. The most widely used polymerization method is the primary amine‐initiated polymerization, which in the absence of side reactions follows eqs 1–3 (Scheme ).…”