Poly(propylene glycol) stabilized gold nanoparticles: An efficient colorimetric assay for ceftriaxone

Raja, Daim Asif; Musharraf, Syed Ghulam; Shah, Muhammad Raza; Jabbar, Abdul; Bhanger, Muhammad Iqbal; Malik, Muhammad Imran

doi:10.1016/j.jiec.2020.03.041

Cited by 20 publications

(14 citation statements)

References 47 publications

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“…In this case, a ratio of 1 : 15 for solutions of PPG and HAuCl 4 ⋅ 3H 2 O (v/v) was found to be optimum, figure 1a. The absorption decreased while going away from this ratio in either direction [22]. The formation of AuNPs at the optimized ratios is further confirmed by AFM imaging, figure 1b.…”

Section: Synthesis and Characterization Of Ppg-aunpssupporting

confidence: 54%

“…Another aspect to be evaluated is the stability of NPs in the presence of different electrolytes. Sodium chloride in a concentration range of 0.01 to 5 M in PPG-AuNPs resulted in a decrease in the intensity of SPR band, which may be attributed to aggregation of the metal ions in the presence of free chloride (Cl −1 ) ions, figure 2b [22]. The absorption band is not affected to a large extent while using NaCl concentration below 0.5 M. NaCl concentrations above this resulted in a significant drop in the intensity of the absorption band.…”

Section: Synthesis and Characterization Of Ppg-aunpsmentioning

confidence: 99%

“…Several different methods have been reported for the formation of AuNPs such as Turkevich method, Brust-Schiffrin, electrochemical method and seeding growth method [18]. In this context, the stabilization of AuNPs with some ligand is an important aspect of their selectivity and sensitivity towards a particular analyte [19][20][21][22]. These stabilizing agents not only prevent the aggregation of the NPs but also induce different functionalities at the surface of MNPs that can be exploited for further specialized applications.…”

Section: Introductionmentioning

confidence: 99%

“…The stabilized AuNPs have exciting surface plasmonic properties and found applications in various research fields such as sensors [23], drug delivery [24], biomedical imaging [25], cancer treatment [26] and in diagnosis and therapy of several other diseases [27]. AuNPs have been employed for the colorimetric detection of biological and chemical compounds due to their large surface area and specific distance-dependent optical properties [12,22,[28][29][30][31][32][33].…”

Section: Introductionmentioning

confidence: 99%

“…In this context, our group have reported numerous chemo-sensors based on metal nanoparticles by using different stabilizing agents for their specific and selective response to different analytes such as insecticides, drugs, metal ions, etc. [22,29,36,38,39]. Among numerous stabilizing agents for NPs, polyethylene glycol (PEG) has been extensively used due to its high biocompatibility, excellent water solubility and non-biofouling characteristics [40].…”

Section: Introductionmentioning

confidence: 99%

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Colorimetric sensing of cephradine through polypropylene glycol functionalized gold nanoparticles

et al. 2021

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The development of metal nanoparticle-based facile colorimetric assays for drugs and insecticides is an emerging area of current scientific research. In the present work, polypropylene glycol was used for stabilization of gold nanoparticles (AuNPs) in a simple one-pot two-phase process and subsequently employed it for the specific detection of cephradine (CPH). The characterization of the prepared PPG-AuNPs was conducted through various analytical techniques such as UV-visible spectrophotometry, Fourier transform infrared spectroscopy, atomic force microscopy (AFM), zeta potential and zetasizer techniques. As the major target of the study, the stabilized PPG-AuNPs were employed for colorimetric detection of CPH and other drugs. Typical wine-red colour of PPG-AuNPs disappeared immediately and surface plasmon resonance band quenched by addition of CPH in the presence of several other interferents (drugs and salts) and in real samples. PPG-AuNPs permitted efficient, selective, reliable and rapid determination in a concentration range of 0.01–120 mM with a detection limit (LoD) of 11.0 mM. The developed sensor has the potential to be used for fast scanning of pharmaceutical formulations for quantification of CPH at production facilities.

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Section: Synthesis and Characterization Of Ppg-aunpssupporting

confidence: 54%

Section: Synthesis and Characterization Of Ppg-aunpsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Colorimetric sensing of cephradine through polypropylene glycol functionalized gold nanoparticles

et al. 2021

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Three‐ligand Co‐assembled 2D Au(I)‐Thiolate Nanosheets

Zhang

Yang

et al. 2022

Chemistry A European J

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Two‐dimensional (2D) Au(I)‐thiolate assemblies are a special type of material that can balance high structural stability and rich surface functionality, which shows promising prospects in both fundamental research and applications. Co‐assembly of multiple ligands is a facile way to further enrich the surface properties and functions, and expand their application potentials. In this work, taking 3‐mercaptopropionic acid (MPA), cysteine (Cys) and 1‐thioglycerol (TGO) as example ligands, we studied in detail the possibility to co‐assemble them into one nanosheet. Although the three ligands have significantly different controllability and pathways when self‐assembling individually with Au(I), they can still be effectively co‐assembled by reacting with HAuCl4 together to obtain three‐ligand nanosheets with good colloidal stability. The key points for successful co‐assembly are also revealed by comparing single‐ and three‐ligand self‐assembly processes, laying a solid foundation for co‐assembly of even more ligands. The easy but powerful strategy for 2D materials with closely‐packed and multiple tunable surface functional groups addresses the surface engineering problem for 2D materials and paves the way for their wider applications in sensing and biomaterials.

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Gold nanoparticle-based selective and efficient spectrophotometric assay for the insecticide methamidophos

Talha,

Raja,

Hussain

et al. 2024

Microchim Acta

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Poly(propylene glycol) stabilized gold nanoparticles: An efficient colorimetric assay for ceftriaxone

Cited by 20 publications

References 47 publications

Colorimetric sensing of cephradine through polypropylene glycol functionalized gold nanoparticles

Colorimetric sensing of cephradine through polypropylene glycol functionalized gold nanoparticles

Three‐ligand Co‐assembled 2D Au(I)‐Thiolate Nanosheets

Gold nanoparticle-based selective and efficient spectrophotometric assay for the insecticide methamidophos

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