Poly(N-vinylcaprolactam) containing solid lipid polymer hybrid nanoparticles for controlled delivery of a hydrophilic drug gemcitabine hydrochloride

Abstract

A hydrophilic polymer, poly(N-vinylcaprolactam), incorporated into solid lipid nanoparticles (SLNs) imparts better encapsulation and controlled release of gemcitabine.

Statistical modeling, optimization and characterization of andrographolide loaded emulgel for its therapeutic application on skin cancer through enhancing its skin permeability

“…ANG 5, ANG 11 AND optimized emulgel ANG 12 (1 g) were placed on the skin surface (in the donor chamber) and carefully covered to avoid evaporation. Aliquots of 1 ml were withdrawn from the receptor chamber at the intervals of 1, 2, 4, 8, 16, and 24 h. The andrographolide content was analyzed by the UV spectrometric method at 225 nm ( Surapaneni and Ambade, 2022 ).…”