Poly(ethylene oxide) adsorption onto chemically etched silicates by Brewster angle reflectivity

Adsorption behavior of a human monoclonal antibody at hydrophilic and hydrophobic surfaces

“…g where, dΓ/dt = adsorption rate; γ = shear rate; L = distance from point of entry to measurement point (cm); D = diffusion coefficient (calculated as 1.99 × 10 -10 for a measured hydrodynamic diameter of 12.17 nm) and; C = concentration (mg/mL). 30 The two parameters in the Leveque equation that could be varied in these experiments were shear rate (γ) and concentration (C), the other parameters remaining constant. To establish transport limited adsorption, we therefore calculated the change in the rate of adsorption (i.e., the linear slope of fluorescence vs time) for increasing concentrations of mAb-1 (maintaining shear at 6 sec -1 ), and increasing shear (for L = 1 cm and a mAb-1 concentration of 0.01 mg/mL).…”

Origins of the Non-DLVO Force between Glass Surfaces in Aqueous Solution

“…After that they were boiled in acidified (pH 2-4) water for 24 h. Such a treatment has been reported, for the Fisherfinest slides, to result in a surface that is primarily silica (37). Cleaning was preformed immediately prior to experimentation.…”

Effect of Particle Size on the Sticking Probability

“…The adsorbed layer properties (layer thickness, surface coverage, and adsorbed mass) were derived from scanning angle reflectometry measurements (14), analyzing the reflectivity in terms of a uniform film model (15)(16)(17). The fixed angle reflectivity signals, in the literature proven to be proportional to the adsorbed amount for thin films up to at least 2 mg/m 2 (10,18), were related to the final properties of the adsorbed layer.…”