Abstract:Polo-like kinases (PLKs) are crucial regulatory factors of the cell cycle process and their dysregulations often cause various diseases including tumorigenesis. Although the PLKs, including PLK1, have been extensively studied and reported, few pan-cancer analyses are attainable. The potential oncogenic roles of PLK1 were thus explored among different cancers according to various online websites and datasets. PLK1 is always overexpressed in many cancers, and there is a significant relationship between its expre… Show more
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