Pollen food allergy syndrome in Turkey: Clinical characteristics and evaluation of its association with skin test reactivity to pollens

Özdemir, Seςil Kepil; Özgüςlü, Selcan

doi:10.12932/ap0881

Cited by 3 publications

(6 citation statements)

References 18 publications

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“…The results from IST and IZM shared some similarities with a previous study. While the overall prevalence of PFAS in Turkey reported by our study was lower than the previously reported 19.3%, 18 kiwi was by far the most common elicitor of PFAS in both studies. 18 Asthma was the most frequent comorbidity of PFASpositive patients in Turkey both in our cohort and in the previous study.…”

Section: Discussioncontrasting

confidence: 88%

“…18 Asthma was the most frequent comorbidity of PFASpositive patients in Turkey both in our cohort and in the previous study. 18…”

Section: Discussionsupporting

confidence: 63%

“…This reflects similar findings as previous studies performed in Italy and Turkey, where kiwi and peach were also reported as the most common elicitors. 17,18 In terms of symptoms, our data show a fast onset and a predominance of oral pruritus. This corroborates current literature, where reactions are described as mainly oral and with a rapid onset.…”

Section: Discussionmentioning

confidence: 56%

“…Studies regarding PFAS in Italy, Turkey, and Spain have been published but show little overlap in methodology and are therefore difficult to compare. [17][18][19] Additionally, different pollens are present in Southern Europe. 20 One of these is cypress pollen, a primary cause of SAR in the Mediterranean.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Heterogeneity of pollen food allergy syndrome in seven Southern European countries: The @IT.2020 multicenter study

Lipp

Şahin

Aggelidis

et al. 2021

Allergy

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show abstract

Section: Discussioncontrasting

confidence: 88%

“…18 Asthma was the most frequent comorbidity of PFASpositive patients in Turkey both in our cohort and in the previous study. 18…”

Section: Discussionsupporting

confidence: 63%

Section: Discussionmentioning

confidence: 56%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Heterogeneity of pollen food allergy syndrome in seven Southern European countries: The @IT.2020 multicenter study

Lipp

Şahin

Aggelidis

et al. 2021

Allergy

View full text Add to dashboard Cite

show abstract

“…Recent pediatric studies from single clinics in UK and Australia showed a prevalence of 48% and 12.9%, respectively [13,22]. Overall, the frequency of PFAS in childhood is higher than previously recognized, and similar to that in adults [23]. The prevalence of PFAS is influenced by local diet, and regional prevalence of atopic diseases [22,24].…”

Section: Epidemiologymentioning

confidence: 99%

Pollen-Food Allergy Syndrome: A not so Rare Disease in Childhood

et al. 2019

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Seasonal allergic rhinoconjunctivitis (SAR) affects millions of people worldwide, particularly in childhood and adolescence. Pollen food allergy syndrome (PFAS) is a common adverse reaction occurring few minutes after the consumption of vegetable foods in patients with pollen-induced SAR. PFAS has rarely been investigated in the pediatric population, as it has been mainly examined as an adult disease. Recent studies suggested that PFAS might be more frequent in childhood than previously recognized. The present review aims to give an overview of the epidemiology, pathophysiology, diagnosis, management and prognosis of PFAS in children with SAR-induced by pollens.

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Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation

Kato

Miyamoto

Takayanagi

et al. 2023

Journal of Immunology Research

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Pollen food allergy syndrome (PFAS) is caused by cross-reactivity with pollen; however, not all-pollen-sensitised individuals develop PFAS, and studies on the characteristics of PFAS development are limited in Japan. We investigated the prevalence and risk factors for the development of PFAS in Japanese children and adolescents sensitised to pollen and their association with pollen-specific IgE levels. The characteristics of PFAS were investigated in patients with allergies aged 3–18 years who visited Dokkyo Medical University Hospital between January 2016 and December 2019. Specific IgE levels for alder, Japanese cedar, ragweed, and orchard grass were measured in patients sensitised to any of the pollens. Patients were categorised into preschool (G1), elementary school (G2), and middle-high school (G3) groups. Overall, 600 patients were enrolled. The prevalence of PFAS was 8.5% in G1, 20% in G2, and 36.3% in G3. Multivariate logistic regression analysis demonstrated strong associations between the risk of developing PFAS and older age (odds ratio (OR), 1.12; 95% confidence interval (CI), 1.06–1.19; P < 0.001 ), seasonal allergy rhinitis (OR, 6.93; 95% CI, 1.59–30.34; P = 0.010 ), and alder sensitisation (OR, 6.20; 95% CI, 2.66–14.49; P < 0.001 ). Spearman’s correlation revealed statistically significant positive correlation between each pollen-specific IgE level; high pollen-specific IgE levels were also a risk factor. The OR for being sensitised to all four species was 36.83 (95% CI, 8.93–151.83, P < 0.001 ) when compared with Japanese cedar alone. Alder was most relevant, with an alder-specific IgE level cutoff value of 2.54 UA/mL. The sensitivity was 78.9%, and the specificity was 70.9%. In conclusion, preschool children develop PFAS with alder sensitisation, and higher pollen-specific IgE levels and increased number of pollen sensitisations are risk factors for developing PFAS.

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Pollen food allergy syndrome in Turkey: Clinical characteristics and evaluation of its association with skin test reactivity to pollens

Abstract: Background: There is limited data regarding pollen food allergy syndrome (PFAS) in Turkey.

Cited by 3 publications

References 18 publications

Heterogeneity of pollen food allergy syndrome in seven Southern European countries: The @IT.2020 multicenter study

Heterogeneity of pollen food allergy syndrome in seven Southern European countries: The @IT.2020 multicenter study

Pollen-Food Allergy Syndrome: A not so Rare Disease in Childhood

Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation

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