Pollen and bee bread expressed highest anti-inflammatory activities among bee products in chronic inflammation: an experimental study with cotton pellet granuloma in rats

Kösedag, Murat; Gülaboğlu, Mine

doi:10.1007/s10787-023-01182-4

Cited by 6 publications

(3 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In another study, it was evidenced that bee pollen exhibited a better anti-inflammatory advantage compared to other bee-derived products; this was due to the administration of 300 mg/kg/day of bee pollen for 7 days in an inflammation model in Dawley rats in which edema was induced, increasing anti-inflammatory cytokines such as IL-4, IL-10, and IL-1RA, and a reduction in pro-inflammatory cytokines such as IL-1β, IL-6, and TNFα [65]. Another study evaluated the anti-inflammatory activity of stingless bee pollen from Melipona fasciculata obtained from three places in the state of Maranhão, Brazil [66].…”

Section: Anti-inflammatory Activitymentioning

confidence: 99%

Chemical Properties and Biological Activity of Bee Pollen

Rodríguez-Pólit,

Gonzalez-Pastor,

Heredia-Moya

et al. 2023

Preprint

View full text Add to dashboard Cite

Pollen, a remarkably versatile natural compound collected by bees for its abundant source of proteins and nutrients, represents a rich reservoir of diverse bioactive compounds with noteworthy chemical and therapeutic potential. Its large range of biological effects has been known and exploited since ancient times. Today, there is an increased interest in finding natural compounds agaisnt oxidative stress, a factor that contributes to various diseases. Recent research has unraveled a multitude of biological activities associated with bee pollen, ranging from antioxidant, anti-inflammatory, antimicrobial, and antifungal properties to potential antiviral and anticancer applications. Comprehending the extensive repertoire of biological properties across various pollen sources remains a challenge. By investigating a spectrum of pollen types and their chemical composition, this review produces an updated analysis of the bioactive constituents and the therapeutic prospects they offer. The findings of this review emphasize the necessity for further exploration and standardization of diverse pollen sources and bioactive compounds that could contribute to the development of innovative therapies.

show abstract

Section: Anti-inflammatory Activitymentioning

confidence: 99%

Chemical Properties and Biological Activity of Bee Pollen

Rodríguez-Pólit,

Gonzalez-Pastor,

Heredia-Moya

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…HBP has been traditionally used in medicinal practices for generations (Khalifa et al., 2021). It has a variety of bioactivities, such as anti‐inflammatory (Kosedag & Gulaboglu, 2023), antibacterial (Çobanoğlu et al., 2023), anticarcinogenic (Di Chiacchio et al., 2022), antiviral (Zarei et al., 2022), hepatoprotective (Mohamed et al., 2021), and anti‐atherosclerotic (Themelis et al., 2019). Furthermore, HBP is a rich source of antioxidants, especially bioactive compounds like flavonoids and polyphenolic substances (Spulber et al., 2018).…”

Section: Introductionmentioning

confidence: 99%

Assessing monofloral bee pollens from Türkiye: Palynological verification, phenolic profile, and antioxidant activity

Çobanoğlu

2024

Journal of Food Science

View full text Add to dashboard Cite

Honey bee pollen (HBP) is a hive product produced by worker bees from floral pollen grains agglutination. It is characterized by its excellent nutritional and bioactive composition, making it a superior source of human nutrition. This study aimed to evaluate the monofloral bee pollen samples, including Cistus, Crataegus monogyna, Cyanus, Elaeagnus angustifolia, Papaver somniferum, Quercus, Salix, Sinapis, and Silybum from Türkiye according to palynological analysis, antioxidant activity, phenolic profiles, and color. The phenolic profiles were detected using ultra‐high performance liquid chromatography coupled with tandem mass spectrometry. Bee pollens were categorized into monofloral, bifloral, and multifloral, underscoring the significance of confirming the botanical source of them depending on palynological analyses. Total phenolic content (TPC) of bee pollens ranged from 4.5 to 14.4 mg gallic acid/g HBP. The samples exhibited antioxidant activity for 2,2′‐azinobis‐(3‐ethylbenzothiazoline‐6‐sulfonic acid) (ABTS •+) ranging from 94.9 to 233.5 µmol trolox/g HBP, whereas lower values were seen for 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH•) ranging from 25.86 to 70.81 µmol trolox/g HBP. A yellowish‐red tint color was also displayed for whole samples, whereas only E. angustifolia bee pollen indicated a darker color (L* = 31.6). Among the phenolic compounds, luteolin, kaempferol, isorhamnetin, rutin, and genistein were the most abundant, and their profiles varied across the samples. It was also observed that TPC, antioxidant activities, and polyphenol composition were higher in samples containing pollen grains of P. somniferum, Quercus, Plantago, and E. angustifolia species.Practical ApplicationThe increasing number of new findings on honey bee pollen is crucial to food science and technology. In this sense, this study offers a robust method for verifying the authenticity and quality of 11 monofloral bee pollens, which is crucial for the food industry. It also identifies potential sources of high‐quality pollen, benefiting producers, and consumers seeking superior bee pollen products.

show abstract

“…The BB (as BP) presents anti-inflammatory, antifungal, anticancer, antimicrobial, antioxidant, and gastroprotective properties, as well as neuroprotective and anti-aging activities [ 24 , 25 , 28 , 29 , 30 , 31 ]. In recent years, there has been a persistent interest regarding the connection between the antimicrobial properties of bee products and antimicrobial resistance to pathogens.…”

Section: Introductionmentioning

confidence: 99%

Bee Bread: A Promising Source of Bioactive Compounds with Antioxidant Properties—First Report on Some Antimicrobial Features

Ilie,

Spoiala,

Geana

et al. 2024

Antioxidants

View full text Add to dashboard Cite

Bee bread has received attention due to its high nutritional value, especially its phenolic composition, which enhances life quality. The present study aimed to evaluate the chemical and antimicrobial properties of bee bread (BB) samples from Romania. Initially, the bee bread alcoholic extracts (BBEs) were obtained from BB collected and prepared by Apis mellifera carpatica bees. The chemical composition of the BBE was characterized by Fourier Transform Infrared Spectroscopy (FTIR) and the total phenols and flavonoid contents were determined. Also, a UHPLC-DAD-ESI/MS analysis of phenolic compounds (PCs) and antioxidant activity were evaluated. Furthermore, the antimicrobial activity of BBEs was evaluated by qualitative and quantitative assessments. The BBs studied in this paper are provided from 31 families of plant species, with the total phenols content and total flavonoid content varying between 7.10 and 18.30 mg gallic acid equivalents/g BB and between 0.45 and 1.86 mg quercetin equivalents/g BB, respectively. Chromatographic analysis revealed these samples had a significant content of phenolic compounds, with flavonoids in much higher quantities than phenolic acids. All the BBEs presented antimicrobial activity against all clinical and standard pathogenic strains tested. Salmonella typhi, Candida glabrata, Candida albicans, and Candida kefyr strains were the most sensitive, while BBEs’ antifungal activity on C. krusei and C. kefyr was not investigated in any prior research. In addition, this study reports the BBEs’ inhibitory activity on microbial (bacterial and fungi) adhesion capacity to the inert substratum for the first time.

show abstract

Pollen and bee bread expressed highest anti-inflammatory activities among bee products in chronic inflammation: an experimental study with cotton pellet granuloma in rats

Cited by 6 publications

References 16 publications

Chemical Properties and Biological Activity of Bee Pollen

Chemical Properties and Biological Activity of Bee Pollen

Assessing monofloral bee pollens from Türkiye: Palynological verification, phenolic profile, and antioxidant activity

Bee Bread: A Promising Source of Bioactive Compounds with Antioxidant Properties—First Report on Some Antimicrobial Features

Contact Info

Product

Resources

About