This article explores the workings of gender expertise inside the institutions of the international governance system as it engages with faith-based actors. Utilizing narratives of gender experts, documentary analysis, and observation, I focus on their encounters regarding gender equality and women's rights with religious leaders, religious actors, and conservative governments. Focusing on episodes where the terms of cultural difference and religion are used synonymously, first, I suggest that these encounters between transnational actors contribute to hegemonic interpretations of these terms. Second, I explore how powerful actors can become even more authoritative in making claims of cultural difference or how the existing distribution of power may be disrupted. I contend that these power relations affect how gender equality is discussed. My goal is to contribute to feminist discussions by highlighting how these transnational interactions disrupt assumptions of Western versus Eastern. I propose to pay attention to these complex and ambiguous processes, in order to challenge ethnocentric and racist discourses but also not take claims of cultural difference at face value.