Polish crossbred pigs’ blood haematological parameters depending on their age and physiological state

Czech, Anna; Grela, Eugeniusz R.; Klebaniuk, Renata; Ognik, Katarzyna; Samolińska, Wioletta

doi:10.22630/aas.2017.56.2.20

Cited by 9 publications

(10 citation statements)

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“…Referent ranges [12] showed that upper and lower referential limit value are different in different age and productivity categories: referential range for hemoglobin, hematocrit, erythrocyte count, lower referential value for MCV, MCH and MCHC and mean value of total proteins and albumin was in increase during weaner pigs category, feeder pigs, gilts and sow. Results given by Czech et al [10] showed linear increase of RBC, Hgb, Hct during age which is in accordance with our results. Same author showed that WBC was lower in piglets than in weaners and both groups of fatteners, with linearly increasing LYM and a decreasing proportion of NEU in the leukocyte population.…”

Section: Discussionsupporting

confidence: 94%

Age-associated and Breed-associated Variations in Haematological and Biochemical Variables in Mangalitsa, Mangalitsa×Durock and Large White Pig

Stevančević

Cincović

Šević

et al. 2019

Acta Scientiae. Vet.

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Background: Research of hematologic and biochemical parameters in pigs is of great importance considering the fact that pigs are used as a model in research of different health disorders in humans. There are many different breeds of pigs that have different health, productive and biologic characteristics that need to be studied. Hematologic and biochemical values can vary dependent on presence of inflammation and infection.The aim of this study was to determine the influence of breed, age and their interactions on hematologic and biochemical parameters on blood of mangalitsa, mangalitsa x durock and Large White pig. Materials, Methods & Results: Experiment included 10 litters of mangalitsa, white variety, mated with mangalitsa boar, 10 mangalitsa litters, and white variety inseminated with durock boar and litters of great Large White inseminated with great Yorkshire boar. Six groups, each include 10 animals were formed and their blood was sampled (3 breeds and 2 age categories). Age groups were formed according to moment of blood sampling. First sample was taken in moment of 30 ± 5 kg of body weight. Second sample was taken when body weight was 100 kg hematologic analyze. Samples were taken with BD Vacutainer®. Complete classic blood analyzes and leucocytes formulas were done by hematology analyzer ADVIA 120 Hematology Siemens, Germany. Biochemical analyze was done by biochemical analyzer A15 BioSystem with their standard colorimetric reagenses. Concentration of total protein, albumin, urea, creatinine, cholesterol, total bilirubin, AST and ALT were determined. Globulin concentration was calculated. Results have showed that hematologic and biochemical parameters are influenced by breed, age and their interaction as: total leukocyte number (age, breed x age), neutrophils number (age, breed), number of monocytes and platelets (age, breed x age), eosinophils number and percentage (age), percentage of neutrophils, percentage of lymphocytes and cholesterol (breed). All of three factors (breed, age breed x age) have affected number of lymphocytes basophils number, % of monocytes, % of basophils, erythrocyte number, hemoglobin concentration, hematocrit, MCV, MCH, MCHC, RDW, protein, albumin, creatinine and ALT. Globulin value varied in function of interaction breed x age. RBC, Hgb, Hct, MCV, MCH, MCHC, total protein albumin, creatinine, and ALT variance can be explained by influence of breed, age and their interaction (η2 = 35-75%).Discussion: Based on results of this study breed and age have significant influence on numerous blood parameters. Besides the differences in mean values of parameters it is proved presence of statistically significant difference in frequencies distributions in function of age and breed. Different age and breed categories have different frequencies distributions of many determined parameters. There is positive correlation between RBC, Hgb, Hct and albumin in all three breed (R2 = 67-84%). Negative correlation was found between WBC and RBC, Hgb, Hct that was statistically significant in mangalitsa breed (R2 = 58-69%) but not in other two breeds. In mangalitsa significant positive correlation was found between globulin and leukocyte number. Given values have showed that during interpretation of lab results breed, age and interactions of hematologic and biochemical parameters need to be considered. Mean values and frequencies distribution differences lead to redefinition of referent range in function of breed and age that requires further research.

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Section: Discussionsupporting

confidence: 94%

Age-associated and Breed-associated Variations in Haematological and Biochemical Variables in Mangalitsa, Mangalitsa×Durock and Large White Pig

Stevančević

Cincović

Šević

et al. 2019

Acta Scientiae. Vet.

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“…Our data showed that gender has no effect on red blood cell parameters, which is consistent with a previous report 12 . The values of RBC, HGB, and HCT were found at a similar level in pigs of the same age, 13 and lower levels than those in older pigs 14 . These value changes are related to age, which could be caused by growth, development, and organ maturation, as well as weight gain.…”

Section: Discussionsupporting

confidence: 92%

“…These value changes are related to age, which could be caused by growth, development, and organ maturation, as well as weight gain. In a Czech study, the values of red blood cell variables increased with age 13 . In addition, these hematologic changes were also related to iron supplementation.…”

Section: Discussionmentioning

confidence: 92%

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Hematologic and biochemical reference intervals for 1‐month‐old specific‐pathogen‐free Landrace pigs

Wang

et al. 2021

Veterinary Clinical Pathol

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Hematologic and biochemical reference intervals (RIs) are important indicators in physiology, pathology, and toxicology research. Accurate biological RIs are essential for early detection and timely diagnosis and treatment of diseases. It is necessary to establish specific RIs for each animal species and strain. Pigs are becoming a more accepted animal model in diverse clinical disease research, such as classical swine fever, erysipelas suis, swine plague, and porcine hepatitis E virus. Pigs are very similar in physiology and anatomy to people; therefore, pigs can be used as xenograft donors. 1,2 Piglets can also be used as an accurate model to study human congenital and hereditary diseases during the newborn period. 3 The specific-pathogen-free (SPF) animals are used as experimental animals due to their internationally recognized standard and can be used in a variety of scientific experiments, including vaccine manufacturing, biological identification, human tumor xenotransplantation, preclinical pharmacology studies, and carcinogenicity trials. 4,5 SPF pigs are suitable for establishing disease models for pig diseases as well as human diseases.

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“…Moreover, the reference ranges for hemoglobin concentration, hematocrit, erythrocyte count, the lower reference value of MCV, MCH and MCHC and the mean value of total proteins and albumin were found to increase in weaner pigs, feeder pigs, gilts and sows. Czech et al (2017) argued that RBC, HGB and Ht values increased linearly with the age of piglets. The linear relationship between red blood cell parameters and body weight can be explained by the increasing blood volume and the amount of hemoglobin and hematocrit in the body (Crichton, 2006).…”

Section: ____________________________________________________________mentioning

confidence: 99%

Reference Values of Hematological, Biochemical and Endocrinological Parameters in the Blood of Piglets Aged 1 and 21 Days

Cincović

Mirkov

Radović

et al. 2020

Contemporary Agriculture

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SummaryThe purpose of this paper is to determine the reference ranges for hematological, biochemical and endocrinological parameters in the blood of the commercial F1 Landrace x Yorkshire and Yorkshire x Landrace piglets aged 1 and 21 days. A total of 72 animals were enrolled in this study. The following reference ranges were determined for the blood parameters considered (day 1 vs. day 21): WBC 10.0-12.4 vs. 11.5-13.7 × 109/L; RBC 3.72-4.06 vs. 5.25-5.73 × 1012/L; HGB 71.4-79.0 vs. 100-110 g/L; HCT 24.4-26.5 vs. 35.7-39.1 %; MCV 64.4-66.0 vs. 72.7-74.8 fL; MCH 20.9-21.7 vs. 24.7-25.6 pg; MCHC 321-329 vs. 367-378 g/L; AST 78.5-98.9 vs. 51.8-66 U/L; ALT 72.5-84.5 vs. 65.9-76.5 U/L; CHOL 2.41-2.71 vs. 3.81-4.27 mmol/L; TGC 1.55-1.93 vs. 1.85-2.25 mmol/L; GLU 5.58-6.24 vs. 5.97-6.67 mmol/L; TPROT 55.2-59.4 vs. 65-69.9 g/L; ALB 13.4-15.1 vs. 27.8-30.9 g/L, GLOB 41.3-44.8 vs. 35.3-40.9 g/L; UREA mmol/L; TBIL 36.6-44.5 vs. 29.4-40.8 μmol/L; ALFAAMYLASE 897-998 vs. 851-949 U/L; LIPASE 74.1-79.7 vs. 88.3-98.1 U/L; CORT 140-196 vs. 41.4-63.8 ng/mL; INSUL 4.04-5.68 vs. 1.71-2.41 μU/L. The RBC, HGB, HCT, MCV, MCH, and MCHC values recorded were found to be higher in the piglets aged 21 days than those in the piglets aged 1 day. The total leukocyte count did not differ between the experimental groups. Lower AST, ALT, globulin, cortisol and insulin values were detected in the piglets aged 21 days than those in the piglets aged 1 day. However, the values of triglycerides, cholesterol, total protein, albumin and lipase were found to be higher in the piglets aged 21 days than those in the piglets aged 1 day. The glucose, alpha amylase and total bilirubin (TBIL) values did not differ significantly between the experimental groups. The Kolmogorov-Smirnov test conducted shows that there are significant differences in the frequency distribution of most of the blood parameters tested in the pigs aged 1 and 21 days, which confirms that a separate reference interval must be determined and applied to the respective piglet ages considered. The establishment of reference values for different age categories can facilitate the assessment of health status and productive performance of farm piglets.

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Polish crossbred pigs’ blood haematological parameters depending on their age and physiological state

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Cited by 9 publications

References 0 publications

Age-associated and Breed-associated Variations in Haematological and Biochemical Variables in Mangalitsa, Mangalitsa×Durock and Large White Pig

Age-associated and Breed-associated Variations in Haematological and Biochemical Variables in Mangalitsa, Mangalitsa×Durock and Large White Pig

Hematologic and biochemical reference intervals for 1‐month‐old specific‐pathogen‐free Landrace pigs

Reference Values of Hematological, Biochemical and Endocrinological Parameters in the Blood of Piglets Aged 1 and 21 Days

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