Poliposis adenomatosa familiar asociada a tumor neuroendocrino de páncreas

Tomé, Ana Pardillos; Andreu, Eduardo Bajador; Orce, A Comín; Córdoba, Francisco Marcilla

doi:10.1016/j.gastrohep.2020.05.023

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Cited by 2 publications

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Gastrointestinal Cancer Syndromes

2023

Counseling About Cancer

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Gastrointestinal Cancer Syndromes

2023

Counseling About Cancer

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Advancements in Early Detection and Screening Strategies for Pancreatic Cancer: From Genetic Susceptibility to Novel Biomarkers

Shah,

Dahiya,

Tiwari

et al. 2024

JCM

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Pancreatic cancer is a rare but lethal cancer due to its biologically aggressive nature, advanced stage at the time of diagnosis, and poor response to oncologic therapies. The risk of pancreatic cancer is significantly higher to 5% in certain high-risk individuals with inherited genetic susceptibility. Screening for pancreatic cancer in these individuals from high-risk groups can help with the early detection of pancreatic cancer as well as the detection of precursor lesions leading to early surgical resection and improved overall outcomes. The advancements in radiological imaging as well as advanced endoscopic procedures has made a significant impact on the early diagnosis, surveillance, and staging of pancreatic cancer. There is also a significant advancement in the development of biomarkers for the early detection of pancreatic cancer, which has also led to the development of liquid biopsy, allowing for microRNA detection in serum and circulating tumor cells. Various societies and organizations have provided guidelines for pancreatic cancer screening and surveillance in high-risk individuals. In this review, we aim to discuss the hereditary risk factors for developing pancreatic cancer, summarize the screening recommendations by different societies, and discuss the development of novel biomarkers and areas for future research in pancreatic cancer screening for high-risk individuals.

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Poliposis adenomatosa familiar asociada a tumor neuroendocrino de páncreas

Cited by 2 publications

References 4 publications

Gastrointestinal Cancer Syndromes

Gastrointestinal Cancer Syndromes

Advancements in Early Detection and Screening Strategies for Pancreatic Cancer: From Genetic Susceptibility to Novel Biomarkers

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