Polio returns to the USA: An epidemiological alert

Rai, Anushree; Uwishema, Olivier; Uweis, Lama; Saleh, Rayyan El; Arab, Sara; Abbass, Mortada; Wellington, Jack; Musabirema, Felix; Adanur, Irem; Onyeaka, Chinyere Vivian Patrick

doi:10.1016/j.amsu.2022.104563

Cited by 7 publications

(6 citation statements)

References 22 publications

(28 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Es bien conocido que la poliomielitis es una enfermedad altamente infecciosa, grave e incurable que causa parálisis muscular, daño en el sistema nervioso y puede desencadenar la muerte (1) ; es conocido también, que las estrategias de inmunización con la vacuna de poliovirus inactivado (IPV) y la vacuna de poliovirus oral atenuado vivo (APO) condujeron a un control drástico de esta enfermedad, considerándose unos de los grandes logros médicos del siglo XX (2) ; no obstante, la poliomielitis causada por el poliovirus salvaje continua siendo endémica en Afganistán y Pakistán (3) . Con los muy raros casos de poliomielitis derivada de vacuna, esta enfermedad parecía estar confinada a estas regiones.…”

Section: Señor Editorunclassified

“…En 2022 Mozambique notificó un primer caso de poliomielitis salvaje con PFA y un brote simultáneo de VDPV-2 (5) . En ese mismo año, Estados Unidos de América notificó un caso de poliomielitis paralítica por VDPV2 (1,3) , presentándose similitudes en estos países pues tanto las cepas salvajes y VDPV se propagan en poblaciones con tasas de vacunación insuficientes.…”

Section: Señor Editorunclassified

“…Asimismo, la figura 1 muestra en los últimos años porcentajes de coberturas preocupantes, incluso menores de 80 %, situación similar a la que se presenta en otros países de América, considerándose a Perú, Haití, y República Dominicana como países de muy alto riesgo de reintroducción de poliovirus salvaje (8) . De igual manera la evidencia indica que mientras la cobertura vacunal esté en declive, existirá la amenaza de algún brote potencial de poliomielitis, especialmente después de la llegada de poliovirus salvaje o derivado de la vacuna (1,4) .…”

Section: Señor Editorunclassified

See 2 more Smart Citations

Riesgo de ingreso de la poliomielitis al Perú: ¿Qué nos dicen las coberturas vacunales?

Quiroz-Ruiz,

Vega-Fernández

2023

Rev Exp Med

View full text Add to dashboard Cite

Section: Señor Editorunclassified

See 1 more Smart Citation

Riesgo de ingreso de la poliomielitis al Perú: ¿Qué nos dicen las coberturas vacunales?

Quiroz-Ruiz,

Vega-Fernández

2023

Rev Exp Med

View full text Add to dashboard Cite

“…Enteroviruses belong to the lineage of the Picornaviridae family and are RNA‐based entities. As per the novel classification system based on genome sequencing techniques, enteroviruses are now subgroups into (HEV‐A), HEV‐B, HEV‐C, and HEV‐D, based on the resemblance in their viral structure protein gene 2 . Neonates experience distinct and often more severe effects when exposed to enteroviruses compared to older children.…”

Section: Introductionmentioning

confidence: 99%

“…As per the novel classification system based on genome sequencing techniques, enteroviruses are now subgroups into (HEV‐A), HEV‐B, HEV‐C, and HEV‐D, based on the resemblance in their viral structure protein gene. 2 Neonates experience distinct and often more severe effects when exposed to enteroviruses compared to older children. As the pendulum of fear swings, the current situation in the region has brought attention and is being closely monitored by competent authorities.…”

Section: Introductionmentioning

confidence: 99%

Outbreak of severe myocarditis in England: Havoc by a harmless virus

Anis,

Basha Shaik,

Tiwari

et al. 2023

Health Science Reports

Self Cite

View full text Add to dashboard Cite

BackgroundThe World Health Organization (WHO) has been alerted to a concerning upsurge of severe myocarditis, an inflammatory heart condition, in neonates within Wales and South West England. The myocarditis cases are being intricately associated with enterovirus infection, belonging to the Picornaviridae family. The concerned pathogen poses a significant global disease burden, with an estimated 10 to 15 million symptomatic cases occurring annually in the United States alone. Neonates are particularly vulnerable with children under the age of one accounting for approximately 40% of enterovirus infections.Material and MethodsA comprehensive literature search was conducted using various databases including ClinicalTrials, Google Scholar, PubMed, ScienceDirect, MEDLINE, and Ovid Resources. The search strategy included utilizing keywords such as “myocarditis,” “Randomized controlled trials (RCTs). Only articles written in English were considered, and selection criteria included relevance to the research objectives, reasonable sample sizes, and robust methodology. In addition to the identified articles, meta‐analyses, animal models and studies, and references from the selected articles were also examined to ensure a comprehensive review of the literature.ResultsTen hospitalized neonates, reported in the United Kingdom (UK), with positive PCR tests were reported to have myocarditis, predominantly caused by coxsackieviruses. The current situation in the region has brought global attention. With this study, we hope to draw attention to the critical aspects of the illness and, more crucially, the present strategies required to control the disease outbreak in England.DiscussionCurrent European Society of Cardiology (ESC) recommendations for the treatment of acute heart failure apply. Emerging research supports the use of immunosuppressive medication in some circumstances. Patients are advised to avoid aerobic activities for several months after healing. Neonatal enterovirus infections can vary in how they respond to IVIG therapy. The majority of enterovirus infections are self‐limited, require no special therapy, and only little supportive care is required.ConclusionThe recent elevation in numbers for reported severe myocarditis in neonates within Wales and South West England, linked to enterovirus infection, poses a significant public health concern. Myocarditis caused by enteroviruses, particularly Group B coxsackieviruses, is associated with significant mortality rates. Diagnosis is supported by non‐invasive techniques and cardiac enzyme blood tests. Treatment modalities primarily involve a palliative approach.

show abstract