Polimiositis y dermatomiositis: incidencia en España (1997-2004)

Vargas-Leguás, Hernán; Selva-O’Callaghan, Albert; Campins-Martí, Magda; Pérez, Eduardo Hermosilla; Grau-Junyent, Josep María; Martínez‐Gómez, Xavier; Rafart, Josep Vaqué

doi:10.1157/13113285

Cited by 34 publications

(6 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The incidence of adult DM is 5.0 to 8.9 per million persons. [ 20 , 21 ] The prevalence of malignancy in DM patients in western countries ranges from 8.6% to 32.0%, [ 11 , 14 ] while in Asians it is 3.8% to 56.0%. [ 9 , 22 ] In our study, the rate was 8.83%, which was in accordance with previous reports.…”

Section: Discussionmentioning

confidence: 99%

Malignancy in dermatomyositis

et al. 2020

View full text Add to dashboard Cite

Dermatomyositis (DM) is an idiopathic inflammatory myopathy that is closely related to malignant diseases. Our study aims to investigate the incidence and predictive factors for occurrence of malignancy among DM patients from Central China. We performed a retrospective, paired, case–control study of 736 DM patients admitted to the First Affiliated Hospital of Zhengzhou University between 2010 and 2017. We paired the 65 patients with malignancy with age-matched and sex-matched patients without malignancy in a ratio of 1:2. Two hundred two patients were finally enrolled and their clinical and laboratory data were collected. The incidence of malignancy in DM patients was 8.83% (65/736). Most malignancies were detected in the most recent 1 year before (9/65, 13.85%) or within 3 years after (40/65, 61.54%) the onset of DM. Males (35/65, 53.85%) and patients aged between 50 and 69 years (43/65, 66.15%) were prone to develop malignancies. Lung cancer (n = 11, 31.43%) was the most common malignancy in male patients, while for females, thyroid, breast and cervical cancer (n = 4 each, 13.33%) were more prevalent. Adenocarcinoma and squamous cell carcinoma (both 18/65, 27.69%) were the top two most common pathological types. Univariate analysis demonstrated that Gottron's sign ( P = .02), dysphagia ( P = .04), albumin (ALB) reduction ( P = .003), aspartate aminotransferase (AST, P = .03), creatine kinase-MB ( P = .02), absence of fever ( P = .02), arthralgia ( P = .04) and interstitial lung disease (ILD, P = .05) were closely related to the occurrence of malignancy. Multivariate analysis revealed the independent risk factors of ALB reduction (odds ratio = 1.546, P = .04) and the protective factor of ILD (odds ratio = 0.349, P = .003). There was no significant difference in the follow-up period between patients with and without ILD ( P = .38). ALB reduction and the absence of ILD were the risk factors for malignancy in DM patients. The protective mechanism of ILD for DM patients needs further study.

show abstract

Section: Discussionmentioning

confidence: 99%

Malignancy in dermatomyositis

et al. 2020

View full text Add to dashboard Cite

show abstract

“…In this first study to do so, the overall incidence of DM was 1.1 per 100,000 person‐years. This estimate falls on the upper end of previous reports, where incidence estimates ranged from 0.1 to 1.5 per 100,000 person‐years (2,14–23). Similarly, our estimated prevalence of 13 per 100,000 was higher than previous prevalence estimates, which ranged from 1.2 to 9.2 per 100,000 (3,17–21,23,24).…”

Section: Discussionmentioning

confidence: 56%

“…Alternatively, incidence of DM may be increasing over time (42,43). However, other studies have not shown this (15,20), and we were not able to assess due to sample size. Most likely, the higher estimates resulted from the large proportion of CADM included in the study population.…”

Section: Discussionmentioning

confidence: 80%

“…While its precise etiology remains unknown, DM has several known risk factors including female sex (2,3), genetics (4–6), ultraviolet radiation (7–9), preceding respiratory diseases (10,11), and other geographic environmental factors (12,13). Current DM incidence estimates range from 1.0 to 15 per million (2,14–23), while prevalence estimates range from 1.2 to 21 per 100,000 (2,3,17–21,23,24). Importantly, both of these estimates are based largely on diagnosis codes rather than verified DM criteria.

This study represents the first population‐based study of dermatomyositis (DM) using the new European Alliance of Associations for Rheumatology/American College of Rheumatology criteria. DM incidence and prevalence estimates fell on the higher end of what has been previously reported, which may reflect either increased capture of clinically amyopathic DM (CADM) cases or a rise in this disease over time. The mortality for myopathic DM was >3‐fold greater than expected but not increased for CADM. Predictive value of DM codes with the new classification criteria remained poor. …”

Section: Introductionmentioning

confidence: 99%

“…While its precise etiology remains unknown, DM has several known risk factors including female sex (2,3), genetics (4)(5)(6), ultraviolet radiation (7)(8)(9), preceding respiratory diseases (10,11), and other geographic environmental factors (12,13). Current DM incidence estimates range from 1.0 to 15 per million (2,(14)(15)(16)(17)(18)(19)(20)(21)(22)(23), while prevalence estimates range from 1.2 to 21 per 100,000 (2,3,(17)(18)(19)(20)(21)23,24). Importantly, both of these estimates are based largely on diagnosis codes rather than verified DM criteria.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Incidence, Prevalence, and Mortality of Dermatomyositis: A Population‐Based Cohort Study

Kronzer

Kimbrough

Crowson

et al. 2022

Arthritis Care & Research

View full text Add to dashboard Cite

Objective. We aimed to determine the population-based incidence, prevalence, and mortality of dermatomyositis (DM) using European Alliance of Associations for Rheumatology (EULAR)/American College of Rheumatology (ACR) criteria.Methods. This population-based cohort study included incident DM from January 1, 1995 to December 31, 2019. We manually reviewed all individuals with at least 1 code for DM or polymyositis to determine if they met EULAR/ ACR criteria, subspecialty physician diagnosis, and/or Bohan and Peter criteria. We age-and sex-adjusted incidence and prevalence estimates to the US non-Hispanic White year 2000 population and estimated prevalence on January 1, 2015. Standardized mortality ratios (SMRs) with 95% confidence intervals (95% CIs) compared observed to expected mortality adjusting for age, sex, and year.Results. We identified 40 cases of verified DM, with 29 cases incident in Olmsted County from 1995 to 2019. The mean age was 57 years, 26 (90%) were female, and 12 (41%) had clinically amyopathic DM (CADM). The median follow-up time was 8.2 years. The overall adjusted incidence of DM was 1.1 (95% CI 0.7-1.5) per 100,000 person-years, and prevalence was 13 (95% CI 6-19) per 100,000. The SMR was significantly elevated among the myopathic DM cases (3.1 [95% CI 1.1-6.8]) but not CADM cases (1.1 [95% CI 0.2-3.3]). The positive predictive value of ≥2 DM codes was only 40 of 82 (49%).Conclusion. This population-based study found that DM incidence and prevalence were higher than previously reported. Mortality was significantly elevated for myopathic DM but not for CADM.The content herein is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

show abstract

Polymyositis, a very uncommon isolated disease: clinical and histological re-evaluation after long-term follow-up

et al. 2014

View full text Add to dashboard Cite

The aim of the present study was to explore whether polymyositis may be considered as an isolated, organ-specific disease or more suitably as a secondary or associated entity. A retrospective re-evaluation of all the muscle biopsies performed at the Hospital Clínic of Barcelona showing histopathological pattern of polymyositis from January 1997 to May 2012 was carried out. The medical records of the patients with the aforementioned pathological pattern were also reviewed. From 1.290 muscle biopsies performed during the period evaluated, 36 with polymyositis pattern were identified. At the time of muscle biopsy, polymyositis pattern was secondary or associated with other disease in 26 patients and was classified as isolated in the remaining ten patients. After pathological re-evaluation and long-term clinical follow-up, only one patient remained with this diagnosis. Overall, the main final diagnosis related to the initial polymyositis pattern was inflammatory myopathy associated with connective tissue disease. Several other associated conditions were also identified. Isolated polymyositis is highly uncommon. Ruling out potential associated or confusing entities, like inclusion body myositis, overlap syndromes, infections, and cancer, is mandatory.

show abstract

Polimiositis y dermatomiositis: incidencia en España (1997-2004)

Cited by 34 publications

References 19 publications

Malignancy in dermatomyositis

Malignancy in dermatomyositis

Incidence, Prevalence, and Mortality of Dermatomyositis: A Population‐Based Cohort Study

Polymyositis, a very uncommon isolated disease: clinical and histological re-evaluation after long-term follow-up

Contact Info

Product

Resources

About