Policy for prevention of Asian rickets in Britain: a preliminary assessment of the Glasgow rickets campaign.

Dunnigan, M. G.; McIntosh, W. B.; Sutherland, George R.; Gardee, Rafik; Glekin, B. M.; Ford, James M.; Robertson, I.

doi:10.1136/bmj.282.6261.357

Cited by 50 publications

(27 citation statements)

References 8 publications

(2 reference statements)

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“…Nine children showed 'marginal' radiological abnormalities and 32 X-rays were judged to be normal. The reduced prevalence of radiological rickets in this study compared with the retrospective study was due to increased supplement consumption following the Greater Glasgow Health Board's campaign against (Dunnigan et al, 1981). The first discriminant function derived from the retrospective study correctly predicted the rachitic category of all three children with definite radiological evidence of rickets.…”

Section: Prospective Studymentioning

confidence: 56%

“…The children were selected from a previous study of 189 children from a single general practice carried out between January and May 1979 to minimize seasonal variation in serum 25-OHD levels (Dunnigan et al, 1981). The sample consisted of children with abnormal levels of serum calcium, inorganic phosphorus or alkaline phosphatase, possible borderline elevations of serum alkaline phosphatase only and normal routine biochemistry (see below).…”

Section: Patientsmentioning

confidence: 99%

“…The presence of rickets in the Glasgow Asian community (Dunnigan et al, 1981) has allowed an assessment of the value of serum calcium (corrected for albumin), inorganic phosphorus, alkaline phosphatase and 25-hydroxy-vitamin D (25-OHD) in predicting the presence of radiological rickets in Asian schoolchildren.…”

Section: Introductionmentioning

confidence: 99%

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Relationships between radiological and biochemical evidence of rickets in Asian schoolchildren

Abdul-Motaal

Gettinby

McIntosh

et al. 1985

Postgraduate Medical Journal

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Summary:One hundred Asian schoolchildren provided evidence of the relationships between radiological and biochemical evidence of rickets in a vitamin D-deficient population. In a retrospective study ofthe X-rays of56 children the variables serum alkaline phosphatase, inorganic phosphorus and age provided a discriminant function which correctly classified 10 of 11 children with radiological evidence of rickets and 44 of 45 children with negative or marginally abnormal X-rays. When the discriminant function was applied to a prospective study of 44 children, three children with radiological evidence of rickets were correctly classified together with 38 of the remaining 41 children with negative or marginally abnormal X-rays. Serum alkaline phosphatase was the most important variable in the discriminant analysis, followed by serum inorganic phosphorus and age. Low levels ofserum 25-hydroxy vitamin D (25-OHD) are of little value in predicting the severity of radiological evidence of rachitic bone disease in a vitamin D-deficient population.

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Section: Prospective Studymentioning

confidence: 56%

Section: Patientsmentioning

confidence: 99%

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Relationships between radiological and biochemical evidence of rickets in Asian schoolchildren

Abdul-Motaal

Gettinby

McIntosh

et al. 1985

Postgraduate Medical Journal

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“…Infantile rickets continues to occur in Asian children in Britain and in a smaller proportion of West Indian children (Gertner & Lawrie, 1977;Dunnigan et al 1981). This is due to lack of utilization of welfare foods and supplements to which the additional risk factors of skin pigmentation, prolonged breast-feeding and lacto-vegetarian diets in later infancy may be added.…”

Section: Nutritional Deficiencies In Infancymentioning

confidence: 99%

“…Two out of five (400/0) children showed biochemical evidence of rickets and 44% had serum 25-OHD concentrations of less than 12.5 nmol/ml ( 5 ng/ml; Dunnigan et al 1981). The impact of osteomalacia on the London Asian community has been reviewed by Stamp (1975) who considered that the condition remained common and was a significant cause of disability among young and middle-aged women.…”

Section: Folic Acid and Vitamin B De$ciency In Asian Subjectsmentioning

confidence: 99%

Nutritional deficiencies among ethnic minorities in the United Kingdom

et al. 1982

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Ethnic minorities in Britain having their origins in the West Indies, the Indian sub-continent (Asian), China and Africa consume diets which differ in varying degree from those of the indigenous population. These minority groups are in general well nourished and almost certainly share obesity with the host population as their commonest nutritional problem. Infantile rickets and iron deficiency anaemia are seen in a small number of the children of all ethnic minorities. Nutritional deficiencies of folic acid and vitamin B,* outside infancy are virtually confined to the Asian population and result from their dietary habit of lacto-vegetarianism. Vitamin D deficiency leading to rickets and osteomalacia is widespread among Asians in Britain. The contribution of dietary factors to rickets and osteomalacia is the subject of current debate. This paper deals mainly with the prevalence, prevention and aetiology of Asian rickets and osteomalacia with particular emphasis on dietary risk factors for the development of these diseases.

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Changing Lifestyles: The Effects on a Balanced Diet

Thomas¹

1988

A Balanced Diet?

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Policy for prevention of Asian rickets in Britain: a preliminary assessment of the Glasgow rickets campaign.

Cited by 50 publications

References 8 publications

Relationships between radiological and biochemical evidence of rickets in Asian schoolchildren

Relationships between radiological and biochemical evidence of rickets in Asian schoolchildren

Nutritional deficiencies among ethnic minorities in the United Kingdom

Changing Lifestyles: The Effects on a Balanced Diet

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