“…# 1998 Academic Press Keratoconjunctivitis sicca (KCS, ' dry eye ') may be induced by nutritional, environmental, toxic, pharmacological, neuronal or hormonal changes and other factors including autoimmune disease such as rheumatoid arthritis McGill, 1985 ;Sansom and Barnett, 1985b ;Carrington et al, 1987b ;Nelson, 1996 ;Schein et al, 1997). The condition is common in humans (Caffery et al, 1996) and in dogs (Kaswan, Pappas and Wall, 1996) : certain breeds of dog being particularly prone to a condition similar to Sjogren's syndrome in man (Grauwels, 1979 ;Sansom and Barnett, 1985a ;Barnett and Sansom, 1985 ;1987 ;Carrington et al, 1987b).…”