Polarity-Specific and Pyrimidine-over-Purine Adaptive Triplex DNA Recognition by a Near-Infrared Fluorogenic Molecular Rotor
Xingli Zeng,
Qiuda Xu,
Rong Lai
et al.
Abstract:Triplex DNA structures have displayed a wide range of
applications
including nanosensing, molecule switching, and drug delivering. Therefore,
it is of great importance to effectively recognize triplex DNA structures
by a simple and highly selective manner. Herein, we found that a near-infrared
fluorogenic probe of NIAD-4 with a molecular rotor (MR) merit can
selectively recognize triplex DNA structures over G-quadruplex, i-motif,
and duplex structures (Tri-over-QID selectivity), which is competent
over the wid… Show more
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