Polarimetric phenomenology of photons with lung cancer tissue

Giakos, G.C.; Marotta, S.; Narayan, Chaya; Petermann, Jeff; Shrestha, Suman; Baluch, J; Pingili, Divya; Sheffer, Daniel B.; Zhang, L; Zervakis, M.; Livanos, George; Kounelakis, M.G.

doi:10.1088/0957-0233/22/11/114018

Cited by 20 publications

(9 citation statements)

References 21 publications

(64 reference statements)

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“…The retardance contrast between healthy and obstructed regions of the bladder would be potentially useful to guide augmentation surgeries and monitoring the tissue functionality following tissue engineering therapies [21]. Mueller polarimetry or polarimetric imaging has furthermore been used to investigate muscles [146], normal and precancerous human cervix [147], oral [13] and lung tissues [148], radiofrequency ablated porcine myocardial tissue [149], skeletal muscle [150], growth of bacteria colonies [151], skin [152][153][154][155] including melanoma [156], animal tissues [144], bladders [137], the orientation of collagen fibres in 3-D space [23], red blood cell suspensions [157], etc.…”

Section: The Biomedical Applications Of Mueller-polarimetric Imagingmentioning

confidence: 99%

Mueller polarimetric imaging for surgical and diagnostic applications: a review

2017

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Polarization is a fundamental property of light and a powerful sensing tool that has been applied to many areas. A Mueller matrix is a complete mathematical description of the polarization characteristics of objects that interact with light, and is known as a transfer function of Stokes vectors which characterise the state of polarization of light. Mueller polarimetric imaging measures Mueller matrices over a field of view and thus allows for visualising the polarization characteristics of the objects. It has emerged as a promising technique in recent years for tissue imaging, improving image contrast and providing a unique perspective to reveal additional information that cannot be resolved by other optical imaging modalities. This review introduces the basis of the Stokes-Mueller formulism, interpretation methods of Mueller matrices into fundamental polarization properties, polarization properties of biological tissues, and considerations in the construction of Mueller polarimetric imaging devices for surgical and diagnostic applications, including primary configurations, optimization procedures, calibration methods as well as the instrument polarization properties of several widelyused biomedical optical devices. The paper also reviews recent progress in Mueller polarimetric endoscopes and fibre Mueller polarimeters, followed by the future outlook in applying the technique to surgery and diagnostics. Tissue polarization properties convey morphological, micro-structural and compositional information of tissue with great potential for label free characterization of tissue pathological changes. Recent progress in tissue polarimetric imaging and polarization resolved endoscopy paved the way for translation of polarimetric imaging to surgery and tissue diagnosis.

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Section: The Biomedical Applications Of Mueller-polarimetric Imagingmentioning

confidence: 99%

Mueller polarimetric imaging for surgical and diagnostic applications: a review

2017

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“…Optical Imaging has got much potential in investigating characteristics of various kinds of materials (biological materials, space materials, polymer materials, etc.) with high particularity [1]- [3]. The ability of polarized light to interact with the matter led to many applications in the field of optical imaging.…”

Section: Introduction and Theoritical Formalismmentioning

confidence: 99%

Design parameters of nanocomposite matrices deposited on silicon substrates, in the optical domain

Giakos

Shrestha

Pingli

et al. 2014

2014 IEEE International Conference on Imaging Systems and Techniques (IST) Proceedings

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The purpose of the study is to optimize the design parameters of nanocomposites matrices deposited on silicon substrate, in the optical domain. Specifically, the interaction of polarized photons with several samples of nanocomposite matrices, consisting of different concentrations of gold nanoparticles dispersed into different concentrations of PV A (poly-vinyl alcohol), deposited on silicon substrates at different spin coating speeds, were studied. Backscattered photons, under co-polarized and cross-polarized transmitter-receiver geometries, were detected and the degree of linear polarization (DOLP) was estimated. The outcome of this study allow us to assess the optimal design parameters of nanocomposites in the optical domain. It is of paramount significance to determine how nanostructures can be effectively integrated into polymer matrices and what new information or enhanced optical properties can be achieved.

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“…The digitalization of pathology can offer the view and analyze the data and samples from any location in the world [1][2][3].The use ofthis method of"remotepathology" can translate the image data easily through the Internet and reduce the manual labor in the labs.Pathologydigitizationeliminates the traditionalmanualmicroscope or the limitations and shortcomings of pathology,for example, it can adjustthe quality of image andacquire as much as possible exposure rate. This also makes thepathological splices easily to storage and retrieval.Further,analysis and process them to extract and diagnosis the related informationof theimage, research the tumormorphology and detect diseases,evaluate the organization'sfunction and the metabolicstage.…”

Section: Introductionmentioning

confidence: 99%

The Digital Tumor Images System Design and its Contour Detection Using an Improved Level Set Algorithm

Ying¹,

Liu²,

Wang³

et al. 2014

Proceedings of the 2014 International Conference on Mechatronics, Electronic, Industrial and Control Engineering

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Because digital diagnostic pathology allows people to acquire, store and analyze pathological information from the images of immunohistochemical glass slides which are scanned to create digital slides, this paper introduced a system design to convert the slides to digital images And it has become one of the most valuable and convenient advancements in technology over the past years. According to the built system, this paper acquired and analyzed the digital pictures from the slides. This analyzed method introduced OSTU segment and an improved fast level set algorithm to outline the tumor contour. Simulations results show that the image analyze algorithm is effective to segment the tumor from the other parts.

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Polarimetric phenomenology of photons with lung cancer tissue

Cited by 20 publications

References 21 publications

Mueller polarimetric imaging for surgical and diagnostic applications: a review

Mueller polarimetric imaging for surgical and diagnostic applications: a review

Design parameters of nanocomposite matrices deposited on silicon substrates, in the optical domain

The Digital Tumor Images System Design and its Contour Detection Using an Improved Level Set Algorithm

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