Polar lipid-enriched milk fat globule membrane supplementation in maternal high-fat diet promotes intestinal barrier function and modulates gut microbiota in male offspring

Abstract

MFGM-PL supplementation to HFD dams improved intestinal development in offspring at weaning via promoting intestinal proliferation, differentiation, tight junctions and modulating gut microbiota, mitigating HFD-induced gut dysbiosis in adulthood.