Poland-Mobius syndrome in an infant girl

Abstract

Mobius syndrome is a rare condition of unclear origin, characterized by a unilateral or bilateral congenital facial weakness with impairment of ocular abduction, which is frequently associated with limb anomalies. Poland described a condition in which there was unilateral absence of pectoralis major muscle and ipsilateral syndactyly. The combination of Poland-Mobius syndrome is rare, with an estimated prevalence 1:500 000. We describe a case of Poland-Mobius syndrome in association with congenital bilateral vocal fold immobility. To our knowldge, this is the first report of such an association between Poland-Mobius syndrome and congenital bilateral vocal fold immobility.

JS-X syndrome: A multiple congenital malformation with vocal cord paralysis, ear deformity, hearing loss, shoulder musculature underdevelopment, and X-linked recessive inheritance

“…Study of relevant literature revealed a few syndromes, which share some characteristics with our studied syndrome, but are nevertheless distinctly different [1][2][3][4][5][6]. Remarkably, CODAS syndrome has some manifestations in common with JS-X syndrome: vocal cord paralysis, helix hypoplasia, hearing loss and craniofacial malformation.…”

Rarely Seen Poland–Moebius Syndrome: A Comprehensive View with Perspective of Pediatric Neurology

“…18 Al-Mazrou et al described a case of Poland-Moebius syndrome in cooccurrence with congenital bilateral vocal fold immobility. 1 In the literature, the majority of the articles about Poland-Moebius syndrome have focused on general clinical findings of the disorder and discussed the cases in terms of the fields apart from a pediatric neurological perspective. This report provides a comprehensive review that includes the differential diagnosis of facial weakness and other cranial nerves involvement from the perspective of pediatric neurology.…”

“…Poland-Moebius syndrome is an infrequent congenital disorder that comprises of both components of Poland and Moebius syndromes. 1 The estimated prevalence of Poland-Moebius syndrome is 1:500,000. 2 Poland syndrome is defined as an absence of pectoralis major muscle, syndactyly, brachydactyly, and hypoplasia of the hands.…”

“…2 Poland syndrome is defined as an absence of pectoralis major muscle, syndactyly, brachydactyly, and hypoplasia of the hands. 1 Poland syndrome affects nearly 1 in 36,000 to 50,000 newborns. 3 Moebius syndrome is characterized by facial weakness combined with ocular movement restriction.…”

Postobstructive Pulmonary Edema following Tonsillectomy/Adenoidectomy in a 2-Year-Old with Poland-Moebius Syndrome

“…In addition to standard risk factors for post-T&A complications, including young age and AHI >5, our patient's Poland syndrome (in the absence of left-sided pectoralis muscles and hypoplasia of ribs 3–5) and Moebius syndrome (affecting his right-sided cranial nerves) undoubtedly impacted his clinical course. Poland syndrome occurs in 1 in 20,000 live births; Poland syndrome combined with Moebius syndrome has an estimated prevalence of 1 : 500,000 [ 3 ]. Poland syndrome has been associated with decreased pulmonary function related to absence of respiratory muscles or decreased muscle function.…”