1981
DOI: 10.1080/09553008114551691
|View full text |Cite
|
Sign up to set email alerts
|

Poisson Goodness-of-fit Tests for Radiation-induced Chromosome Aberrations

Abstract: Asymptotic and exact Poisson goodness-to-fit tests have been reviewed with regard to their applicability in analysing distributional properties of data on chromosome aberrations. It has been demonstrated that for typical cytogenetic samples, i.e. when the average number of aberrations per cell is smaller than one, results of asymptotic tests, especially of the most commonly used u-test, differ greatly from results of corresponding exact tests. While the u-statistic can serve as a qualitative index to indicate … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

0
7
0

Year Published

1983
1983
2018
2018

Publication Types

Select...
6

Relationship

1
5

Authors

Journals

citations
Cited by 14 publications
(7 citation statements)
references
References 11 publications
0
7
0
Order By: Relevance
“…The case of y << 1 is usual at low doses in cytogenetic samples, and then the most likely outcome is that the total number of aberrations observed is made up exclusively of cells with only one aberration in it, even for large n. For small counts the true distribution of u is therefore heavily skewed to the right and does not approach the normal distribution for any practically feasible n (Merkle 1981). Graphically, the assumption of normal distribution of D-statistic (the ustatistic is based in this asymptotic approximation) can be appreciated in the Figure 1 for n = 500 and in the Figure 2 for n = 50.…”
Section: Asymptotic U-test In the Case Of Small Counts Of Aberrationsmentioning
confidence: 99%
See 4 more Smart Citations
“…The case of y << 1 is usual at low doses in cytogenetic samples, and then the most likely outcome is that the total number of aberrations observed is made up exclusively of cells with only one aberration in it, even for large n. For small counts the true distribution of u is therefore heavily skewed to the right and does not approach the normal distribution for any practically feasible n (Merkle 1981). Graphically, the assumption of normal distribution of D-statistic (the ustatistic is based in this asymptotic approximation) can be appreciated in the Figure 1 for n = 500 and in the Figure 2 for n = 50.…”
Section: Asymptotic U-test In the Case Of Small Counts Of Aberrationsmentioning
confidence: 99%
“…Another application of the exact D-test was performed by (DuFrain et al 1980) to over-dispersed data of chromosomal aberrations in human lymphocytes exposed to α-particles. (Merkle 1981) applied the exact test to investigate the behavior of several test for the Poisson goodness of fit. A computer program for the exact test was published in (Papworth 1983) based on the test proposed by (Fisher 1950) and the existence of the program was mentioned in (Merkle 1981) as a note added in proof.…”
Section: Application Of the Exact D ′ And L ′ Tests To Chromosomal Abmentioning
confidence: 99%
See 3 more Smart Citations