Poisoning due to psychotropic drugs

Vale, J. A.; Meredith, Tammy

doi:10.1016/0165-0327(82)90028-3

Cited by 3 publications

(3 citation statements)

References 92 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In none ofthe cases was application ofspecific antiarrhythmic therapy necessary. This low incidence of cardiac arrhythmias is e10se to that found in other studies (20,21,29,35,36,37,41,42).…”

Section: Resultssupporting

confidence: 83%

“…These figures suggest that, at present, there may be geographically different trends in the incidence of selfpoisoning with TNAD in Germany. Even so, the figures from Berlin and Munich are lower than those reported by other authors (20,2,26,28,29). While figures from Switzerland and Denmark are comparable to or even lower than the figures from Berlin and Munich (14, 31), a much higher incidence of TNAD poisonings is reported by British, American, and Australian authors.…”

Section: Resultsmentioning

confidence: 63%

“…Death, after six weeks in hospital, was due to a complicated abscess. Over the period 1976 to 1980, an annual average of 2.9 %of the acute poisonings treated in the resuscitation center involved TNAD, a small number compared with reports by other authors (2,(24)(25)(26)(27)(28)(29)(30). However, the observation that the incidence of antidepressant overdosage did not appear to be on the increase is in agreement with other studies (27,28,20,31 ).…”

Section: Resultsmentioning

confidence: 85%

See 2 more Smart Citations

Tricyclic Neuroleptic and Antidepressant Overdose: Epidemiological, Electrocardiographic, and Clinical Features* - A Survey of 92 Cases

Kresse-Hermsdorf

Müller‐Oerlinghausen²

1990

Pharmacopsychiatry

View full text Add to dashboard Cite

From 1976 to 1980, there were 3,193 admissions due to acute drug overdosage at the resuscitation centre of the Rudolf-Virchow-Hospital, Free University of Berlin. The frequency and the characteristics of selfpoisoning with antidepressants and low-potency neuroleptic drugs (mainly perazine and thioridazine) were determined. These drugs were involved in 92 cases (3%) during this five-year period. Amitriptyline--in combination with a benzodiazepine--was the most common antidepressant taken by the patients. Ten of the patients required assisted ventilation. Complete ECG recordings were carried out in 24 patients. The most common abnormality was a prolonged QTc interval (21 patients) followed by a QRS duration of 0.11 seconds or longer (17 patients). Sinus tachycardia was present in half of the cases. In no cases did the medical records describe convulsions or cardiac arrhythmias requiring special treatment. The percentage of patients showing ECG changes and respiratory depression was higher when other drugs such as ethanol were ingested along with antidepressants than when only antidepressants were taken. One patient died after six weeks in hospital due to a complicated abscess. From 1976 to 1980, the incidence of antidepressant selfpoisoning was relatively low compared with findings from other studies. Data from other studies suggest that, in the period 1980-1987, there was an increase in the incidence of antidepressant selfpoisoning, at least in the West Berlin and Munich areas. However, these figures are much lower than those reported by British, American, and Australian authors.

show abstract

Section: Resultssupporting

confidence: 83%

Section: Resultsmentioning

confidence: 63%

Section: Resultsmentioning

confidence: 85%

See 1 more Smart Citation

Tricyclic Neuroleptic and Antidepressant Overdose: Epidemiological, Electrocardiographic, and Clinical Features* - A Survey of 92 Cases

Kresse-Hermsdorf

Müller‐Oerlinghausen²

1990

Pharmacopsychiatry

View full text Add to dashboard Cite

show abstract

Hyperpyrexia following psychotropic drug overdose

Peebles-Brown¹

1985

Anaesthesia

View full text Add to dashboard Cite

show abstract

4. Arrhythmogenic Right Ventricular Dysplasia (ARVD): An Overlooked and Underdiagnosed Condition?

et al. 1997

View full text Add to dashboard Cite

We present three cases of arrhythmogenic right ventricular dysplasia causing or contributing to sudden death. These cases serve to highlight the range of clinical presentations and histological features seen in this rare and poorly understood condition. Arrhythmogenic right ventricular dysplasia (ARVD) is a cardiomyopathy characterized by a normal or mild increase in heart weight with right-sided heart dilatation. Typically a proportion of the right ventricular muscle is replaced by fat and fibrous tissue. Clinically, the condition is characterized by episodes of ventricular tachycardia and global dyskinesia of the right ventricle. It may cause ventricular fibrillation and sudden death, especially in young persons engaged in strenuous exercise or who experience severe emotional outburst. The aetiology of the condition is unknown, although it has been noted to show familial clustering in some cases.

show abstract

Poisoning due to psychotropic drugs

Cited by 3 publications

References 92 publications

Tricyclic Neuroleptic and Antidepressant Overdose: Epidemiological, Electrocardiographic, and Clinical Features* - A Survey of 92 Cases

Tricyclic Neuroleptic and Antidepressant Overdose: Epidemiological, Electrocardiographic, and Clinical Features* - A Survey of 92 Cases

Hyperpyrexia following psychotropic drug overdose

4. Arrhythmogenic Right Ventricular Dysplasia (ARVD): An Overlooked and Underdiagnosed Condition?

Contact Info

Product

Resources

About