Point-of-Care Testing: General Aspects

Ferreira, Carlos Ernesto Santos; Guerra, João Carlos Campos; Slhessarenko, Natasha; Scartezini, Mariléia; França, Carolina Nunes; Colombini, Marjorie Paris; Berlitz, Fernando; Machado, Antonia M O; Campana, Gustavo Aguiar; Faulhaber, Adriana C.L.; Galoro, César Alex de Oliveira; Dias, Claudia Mazza; Shcolnik, Wilson; Martino, Marinês Dalla Valle; Cesar, Katia R.; Sumita, Nairo Massakazu; Mendes, Maria Elizabete; Faulhaber, Marcelo H W; Pinho, João Renato Rebello; Barbosa, Ismar Venâncio; Batista, Marcelo Costa; Khawali, Cristina; Pariz, Vitor M; Andriolo, Adagmar

doi:10.7754/clin.lab.2017.170730

Cited by 38 publications

(35 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…POCT can be used to improve patient flow within the clinical setting and may even provide indirect cost effectiveness advantages compared to centralized laboratory testing, considering increased resource management and more efficient patient care [3,34]. Shortening the turnaround time is another asset of the HiF system, specially when delays compromises the patient's health: on an intensive care unit setting, the time of analysis shows great influence over a physician's conduct [35], thus the patient can greatly benefit from a faster, yet precise result.…”

Section: Discussionmentioning

confidence: 99%

Analytical Accuracy and Clinical Agreement of a Novel Internet of Things and AI-based Point-of-Care Testing Laboratory

Malucelli

Alves

Saldanha

et al. 2021

Preprint

Self Cite

View full text Add to dashboard Cite

Point-of-care testing (POCT) offers several advantages over traditional laboratory testing. Offering less invasive testing with a faster turnaround time is not enough if not associated with an acceptable level of accuracy. Here, we show the analytical validation behind the multi-analyte POCT immunochromatography analyser, Hilab Flow (HiF). Analyses from 4,518 clinical samples were compared to College of American Pathologists accredited laboratories for ten quantitative and thirteen qualitative exams. Compatibility between methods was evaluated in terms of association/correlation and clinical agreement. Strong correlation/ concordance was observed between quantitative (CHOL, HDL-c, TG, HbA1c, Glycemia, 25-Hydroxy Vitamin D, TSH, Uric Acid, Creatinine, Urea) and qualitative methods (COVID-19 IgG/ IgM, Beta-hCG, Syphilis, Anti-HBsAg, Zika IgG/ IgM, Influenza A/B, HIV, HCV, HBsAg, Dengue NS1, COVID-19 Ag, Dengue IgG/ IgM, PSA). Approval criteria was obtaining a kappa agreement > 0.8 or a Pearson correlation > 0.9 depending on the exam. Overall percentage agreement was greater than 95% for all exams, indicating a good clinical agreement to gold-standard laboratory-based tests. Results indicate all exams are suitable for POCT and present a reliable performance. Data support the analyser is a useful tool to aid decision-making at the clinical setting, with potential to contribute with healthcare solutions in diagnostic medicine worldwide.

show abstract

Section: Discussionmentioning

confidence: 99%

Analytical Accuracy and Clinical Agreement of a Novel Internet of Things and AI-based Point-of-Care Testing Laboratory

Malucelli

Alves

Saldanha

et al. 2021

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

“…POCT refers to a clinical test that can be performed on the patient's bedside without the need for complicated equipment and specialized laboratory examiners. It samples on-site and analyzes immediately, eliminating the complicated processing procedures required for sample testing in the laboratory and quickly obtaining medical test results [129]. At present, the most commonly used POCT include blood glucose test paper and urine pregnancy test paper.…”

Section: Detection Methods Based On Point-of-care Testing (Poct)mentioning

confidence: 99%

Electrochemical Detection and Point-of-Care Testing for Circulating Tumor Cells: Current Techniques and Future Potentials

Han

Sun

et al. 2020

Sensors

View full text Add to dashboard Cite

Circulating tumor cells (CTCs) are tumor cells that escaped from the primary tumor or the metastasis into the blood and they play a major role in the initiation of metastasis and tumor recurrence. Thus, it is widely accepted that CTC is the main target of liquid biopsy. In the past few decades, the separation of CTC based on the electrochemical method has attracted widespread attention due to its convenience, rapidness, low cost, high sensitivity, and no need for complex instruments and equipment. At present, CTC detection is not widely used in the clinic due to various reasons. Point-of-care CTC detection provides us with a possibility, which is sensitive, fast, cheap, and easy to operate. More importantly, the testing instrument is small and portable, and the testing does not require specialized laboratories and specialized clinical examiners. In this review, we summarized the latest developments in the electrochemical-based CTC detection and point-of-care CTC detection, and discussed the challenges and possible trends.

show abstract

“…Every medical technology has its strengths and weaknesses. Depending on the affected group, advantages and disadvantages of bedside diagnostics can be further observed from the patient, healthcare workers and government or healthcare funder perspective [ 12 , 13 , 14 , 15 ], see Table 1 .…”

Section: Point-of-care Diagnosticmentioning

confidence: 99%

Diagnostic Modalities in Critical Care: Point-of-Care Approach

et al. 2021

View full text Add to dashboard Cite

The concept of intensive care units (ICU) has existed for almost 70 years, with outstanding development progress in the last decades. Multidisciplinary care of critically ill patients has become an integral part of every modern health care system, ensuing improved care and reduced mortality. Early recognition of severe medical and surgical illnesses, advanced prehospital care and organized immediate care in trauma centres led to a rise of ICU patients. Due to the underlying disease and its need for complex mechanical support for monitoring and treatment, it is often necessary to facilitate bed-side diagnostics. Immediate diagnostics are essential for a successful treatment of life threatening conditions, early recognition of complications and good quality of care. Management of ICU patients is incomprehensible without continuous and sophisticated monitoring, bedside ultrasonography, diverse radiologic diagnostics, blood gas analysis, coagulation and blood management, laboratory and other point-of-care (POC) diagnostic modalities. Moreover, in the time of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, particular attention is given to the POC diagnostic techniques due to additional concerns related to the risk of infection transmission, patient and healthcare workers safety and potential adverse events due to patient relocation. This review summarizes the most actual information on possible diagnostic modalities in critical care, with a special focus on the importance of point-of-care approach in the laboratory monitoring and imaging procedures.

show abstract

Point-of-Care Testing: General Aspects

Cited by 38 publications

References 0 publications

Analytical Accuracy and Clinical Agreement of a Novel Internet of Things and AI-based Point-of-Care Testing Laboratory

Analytical Accuracy and Clinical Agreement of a Novel Internet of Things and AI-based Point-of-Care Testing Laboratory

Electrochemical Detection and Point-of-Care Testing for Circulating Tumor Cells: Current Techniques and Future Potentials

Diagnostic Modalities in Critical Care: Point-of-Care Approach

Contact Info

Product

Resources

About