Abstract:Background
Several assays reliably measure cerebrospinal fluid (CSF) total tau (t‐tau) protein for Alzheimer’s diseases (AD) diagnosis. However, CSF sampling is invasive and hampers availability of biomarker testing in AD. Therefore, less invasive blood t‐tau assays are needed, preferably on different platforms to enable implementation in different clinical settings. Point‐of‐care (POC) platforms enable the development of practical and easily implemented assays. Here, we aim to develop and compare two blood t‐… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.