Point-of-Care Diagnostic Testing in Urgent Cardiac Care

Portable microfluidic plasmonic chip for fast real-time cardiac troponin I biomarker thermoplasmonic detection

“…In response to this specific demand and to overcome the major drawbacks of conventional detection methods, considerable attention has been focused on the development of Point-of-Care (PoC) devices, which present advantages such as specificity, efficiency, precision, portability, as well as ease-ofuse and low costs, leading towards personalized medicine in terms of medical event prediction, appropriate treatment and improved prognosis. 16 In particular, microfluidic PoC devices are able to rapidly detect biomarkers with high efficiency due to their increased sensitivity, while considerably reducing the cost of testing -no need for well-trained operators and complex laboratory equipment, reagents and sample volume and analysis time. 17,18 The coupling of microfluidics with plasmon-based high throughput techniques such as Localized Surface Plasmon Resonance (LSPR), Surface Enhanced Raman Spectroscopy (SERS), etc.…”