“…Surprising features of the cases here described are: (1) there appears to have been no previous description of similar cases in any medical book or journal, despite the high incidence of erythema ab igne in this country; and (2) in this small number two of the four patients with carcinoma had been cured of cancer of other organs some years previously, while the other two had skin changes compatible with a diagnosis of poikilodermia atrophicans vasculare, a disease which may be the first sign of an internal carcinoma, leukaemia, or mycosis fungoides, but may also be found in subjects with hereditary ectodermal defects, such as existed in Case 3. Exposure to sunlight and to cold seems to have played a part in some cases of this type of poikilodermia, and Downing et al (1947) have suggested that physical factors might well be precipitating factors.…”