PO-374 LINC00152 long non-coding RNA promotes the proliferation of SW480 colon carcinoma cells through regulation of cell cycle and WNT signalling pathway
Abstract:Material and methods We analysed DNAmethylation of 1264 genes encoding miRNAs in 26 BCVY samples and 15 samples from BCO using the 'Illumina Infinium MethylationEPIC BeadChip' array. Methylation differences were assessed using Wilcoxon Rank Sum test. Differences observed were validated using two independent populations:Flower et al 2015 and The Genome Caner Atlas (TCGA) methylation datasets. Expression of miRNAs regulated by CpG sites differently methylated were analysed in a meta-analysis using data from Clar… Show more
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