Abstract:cells from regional LNs of melanoma patients, irrespective of LN involvement. Conversely, the expression of inhibitory receptors did not correlate with NK cell cytotoxicity except for CD158b that after control CM treatment showed negative correlation. Conclusion Antitumor potential of immune cells from regional LNs induced with IL-2 and IL-15 cytokine treatments may indicate the importance of this immune cell population in the development of therapeutic strategies that involve local cytokine application.
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