PO-1111 Is Calendula useful for radiation dermatitis in breast cancer? A single-centre clinical trial.

Valls, P. Blasco; Prieto, Carlos; Rodríguez, M. Fernández; Russo, G.; Salud, N. Mut; Sánchez, Rodrigo Alberto Hoyos; Castillo, Iván; érez, P.

doi:10.1016/s0167-8140(21)07562-9

Cited by 2 publications

(4 citation statements)

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“…According to Pommier et al and Valls et al, C. officinalis was effective in preventing dermatitis. They suggested that C. officinalis should be offered to patients undergoing irradiation (Pommier et al, 2004; Valls et al, 2021). However, two other studies demonstrated no difference between placebo cream (including Essex cream and Sorbolene) and C. officinalis cream in patients with radiodermatitis (Sharp et al, 2013; Siddiquee et al, 2020).…”

Section: Resultsmentioning

confidence: 99%

“…Another study examined the effect of C. officinalis topical ointment on 59 breast cancer patients and also concluded that calendula is useful for the treatment of radiation dermatitis (Valls et al, 2021). However, a randomized, blinded trial conducted in 2013 found no difference between calendula and placebo (Essex cream) (Sharp et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

“…Hoopfer et al found no evidence that aloe vera cream could reduce the severity of the skin reaction (Hoopfer et al, 2015). Valls et al, 2021). However, two other studies demonstrated no difference between placebo cream (including Essex cream and Sorbolene) and C. officinalis cream in patients with radiodermatitis (Sharp et al, 2013;Siddiquee et al, 2020).…”

Section: Aloe Veramentioning

confidence: 99%

Section: Herbal Medicinementioning

confidence: 99%

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The efficacy of medicinal plant preparations in the alleviation of radiodermatitis in patients with breast cancer: A systematic review of clinical trials

Baharara

Rahsepar

Emami

et al. 2023

Phytotherapy Research

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Radiodermatitis in breast cancer patients varies from mild irritation to life‐threatening lesions. Several studies suggest a role for topical corticosteroid ointments in the treatment of radiodermatitis. Yet, to avoid the adverse effects of corticosteroids, many authors recommend the use of topical herbal products instead. The therapeutic role of herbal treatments has yet to be fully understood. This systematic review evaluates the role of topical or oral herbal medicines in radiodermatitis prevention and treatment. A systematic search of four databases (Embase, PubMed, Web of Science, and Scopus) was performed without language and time restrictions from their inception until April 2023. The bibliographies of potential articles were also searched manually. Studies evaluated and compared the effects of herbal preparations with the control group, on dermatitis induced by radiotherapy for breast cancer. The Cochrane risk of bias tool was used to assess the included studies. Thirty‐five studies were included in the systematic review. Studies which used herbal drugs including topical and oral formulations were evaluated. Herbal monotherapy and combination therapy were reported, and their effects on radiodermatitis were explained in the systematic review. In conclusion, henna ointments, silymarin gel, and Juango cream were reported to reduce the severity of radiodermatitis. These agents should be considered for radiodermatitis prophylaxis and treatment. The data on aloe gel and calendula ointment were conflicting. Further randomized controlled trials of herbal medications and new herbal formulations are required to determine their effects on breast cancer radiodermatitis.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Aloe Veramentioning

confidence: 99%

Section: Herbal Medicinementioning

confidence: 99%

See 2 more Smart Citations

The efficacy of medicinal plant preparations in the alleviation of radiodermatitis in patients with breast cancer: A systematic review of clinical trials

Baharara

Rahsepar

Emami

et al. 2023

Phytotherapy Research

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Ergänzende Maßnahmen in der Strahlentherapie: Nebenwirkungen und Spätfolgen vorbeugen und behandeln

Steinmann,

Savaş,

Märtens

et al. 2023

Zeitschrift für Komplementärmedizin

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SummaryDie Strahlentherapie ist eine wichtige Behandlungssäule in der Krebstherapie, jedoch auch mit Nebenwirkungen und Spätfolgen verbunden. Ergänzende Maßnahmen können diese effektiv vorbeugen und lindern. Dabei werden verschiedene pflanzliche Präparate, Vitamine, Spurenelemente oder weitere Nahrungsergänzungsmittel zur Behandlung der radiogenen Dermatitis (Aloe vera, Calendula), Mukositis (Honig, Sanddornfruchtfleischöl), Proktitis (Vitamin D, Probiotika, Selen) oder des Hirnödems (Boswelliaserrata) eingesetzt. Maßnahmen wie Sport und regelmäßige Entspannungsübungen können die allgemeine Leistungsfähigkeit und Befindlichkeit verbessern. Des Weiteren sind mögliche Wechselwirkungen zwischen komplementären Verfahren und der Strahlentherapie zu berücksichtigen.

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PO-1111 Is Calendula useful for radiation dermatitis in breast cancer? A single-centre clinical trial.

Cited by 2 publications

References 0 publications

The efficacy of medicinal plant preparations in the alleviation of radiodermatitis in patients with breast cancer: A systematic review of clinical trials

The efficacy of medicinal plant preparations in the alleviation of radiodermatitis in patients with breast cancer: A systematic review of clinical trials

Ergänzende Maßnahmen in der Strahlentherapie: Nebenwirkungen und Spätfolgen vorbeugen und behandeln

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