Pns64 Health-Related Quality of Life Inequalities by Gender Identity and Sexual Orientation and Role of Depression as an Explanatory Variable

Abstract

mortality rates associated with stage III detection, and (2) mortality rates were stageshifted from stage IV to III, stage III to II, and stage II to I detection and assigned the associated mortality rates. Results: In a hypothetical cohort of 100,000 persons, 1,233 were estimated to be diagnosed with any cancer, of whom 414 were expected to die within 5 years. Of 229 diagnosed with metastatic cancer, 174 were expected to die within 5 years. If all metastatic cancers were diagnosed at stage III, 79 fewer cancer deaths would be expected, a reduction of 45% in the deaths due to metastatic cancer, or 19% of all cancer deaths. If all metastatic cancers were diagnosed at stage III, all stage III diagnosed at stage II, and all stage II diagnosed at stage I, 131 fewer cancer deaths would be expected, a reduction of 32%. Conclusions: Diagnosing cancer before metastasis, even at stage III, could result in substantial reductions in the overall cancer mortality rate.