Pneumonokoniose durch Zementstaub

Doerr, Wilhelm

doi:10.1007/bf00957587

Cited by 19 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The prevalence of respiratory disease of cement industry workers in different countries varied, and some authors have attempted to correlate the noxious effects of cement with its free silica content (Sayers et al, 1937;Gardner et al, 1939;Giuliani and Belli, 1955;Jenny et al, 1960;Einbrodt and Hentschel, 1966;Hublet, 1968;Parkes, 1974). Doerr (1952) reported pulmonary pathological findings at necropsy in a man exposed to cement dust, although he was also exposed to quartz dusts, and a pseudotumoral silicosis cannot be excluded considering the silicotic-type concentric arrangement of collagen bundles in the lesions (Doerr, 1952;Pimentel and Gomes, 1973;Parkes, 1974). As to mica, although radiographic and functional respiratory abnormalities have been observed in the survey of workers exposed (Middle- Table 1).…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, there are few references to the pulmonary histopathology (Doerr, 1952;Vorwald, 1960;Pimentel and Gomes, 1973), and other possible causes of pneumoconiosis were not excluded in some reports (Doerr, 1952;Vorwald, 1960). There is also some controversy over the experi-'Present address: Laboratory of Pathophysiology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014, U.S.A. mental pathogenic effects of cement and mica (Lemon and Higgins, 1935;Baetjer, 1947;King et al, 1947King et al, , 1950Einbrodt and Hentschel, 1966;Tripsa and Rotaru, 1966;Pimentel and Gomes, 1973).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Pulmonary and hepatic granulomatous disorders due to the inhalation of cement and mica dusts.

Pimentel¹,

Menezes²

1978

Thorax

View full text Add to dashboard Cite

. (1978). Thorax, 33,[219][220][221][222][223][224][225][226][227]. Pulmonary and hepatic granulomatous disorders due to the inhalation of cement and mica dusts. Hepatic and pulmonary granulomas were recognised in two workers exposed respectively to Portland cement and to muscovite dusts. The pulmonary lesions in the patient exposed to cement consisted of histiocytic granulomas and irregular fibrohyaline scars, and in the patient exposed to mica of a diffuse thickening of all interalveolar septa due to new formation of reticulin and collagen fibres and proliferation of fibroblasts and histiocytes. In the liver the following pathological findings were observed: focal or diffuse swelling of sinusoidal lining cells, sarcoid-type granulomas, and, in the case of mica exposure, perisinusoidal and portal tract fibrosis. Abundant inclusions of the inhaled material were identified within the pulmonary and hepatic lesions by histochemical and x-ray diffraction techniques.The inhalation of dusts containing silicon is known to produce different kinds of pneumoconiosis. Although free silica is sometimes the only pathogenic dust inhaled, in most situations there is exposure to silicates (for example, mica, asbestos, kaolin, talc) or to mixed dusts of free or combined silica and other inorganic dusts such as cement. The pathological findings produced by the latter type of dusts do not mimic the typical pattern of silicosis, and their diagnosis is based on the occupational history of the patient and on the identification of the inhaled foreign material within the lesions.The effects of cement and mica dusts on the human respiratory tract have been recognised in epidemiological surveys (Middleton, 1936;Sayers et al., 1937;Gardner et al., 1939;Dreesen et al., 1940;Vestal et al., 1943;Giuliani and Belli, 1955; Jenny et al., 1960Hublet, 1968 Kalacic, 1973).Nevertheless, there are few references to the pulmonary histopathology (Doerr, 1952;Vorwald, 1960;Pimentel and Gomes, 1973), and other possible causes of pneumoconiosis were not excluded in some reports (Doerr, 1952;Vorwald, 1960). There is also some controversy over the experi- mental pathogenic effects of cement and mica (Lemon and Higgins, 1935;Baetjer, 1947;King et al., 1947King et al., , 1950Einbrodt and Hentschel, 1966;Tripsa and Rotaru, 1966;Pimentel and Gomes, 1973).In addition to causing pulmonary lesions, exposure to pathogenic dusts may produce hepatic granulomas, as described in silicosis (Cisno et al., 1971), berylliosis (Chesner, 1950), and vineyard sprayer's lung (Pimentel and Menezes, 1975 A 46-year-old woman had been exposed to the inhalation of mica dust during grinding and packaging operations for seven years. In March 1971 she was admitted to hospital for dyspnoea on exertion, progressive weakness, and loss of weight. Symptoms had appeared two years before admission after a 'common cold'. There was no previous history of respiratory diseases. During this period antituberculosis drugs (streptomycin and isoniazid) were used without benefit; the sputum was pers...

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Pulmonary and hepatic granulomatous disorders due to the inhalation of cement and mica dusts.

Pimentel¹,

Menezes²

1978

Thorax

View full text Add to dashboard Cite

show abstract

“…Deposition of silica particles in the liver (Giese 1931, Kalbfleisch 1933, Ritterhoff 1941, Lynch 1942, Cioni 1943, Doerr 1952, Ambrosi 1965, Cisno, Azzalini & Camagna 1971, Pachecho & Nuno 1975 and spleen (Askanazy 1901, 1906, Entin 1915-16, Edinger 1932, Belt 1939, Albertini, Brandenberger & Ruttner 1947, Biasi 1949, Ambrosi 1966 are well recognized features of severe silicosis. In these sites the silica particles evoke tissue reactions comparable to those in the lungs (Belt 1939, Ambrosi 1966, Pachecho & Nuno 1975.…”

Section: Introductionmentioning

confidence: 99%

Silicotic lesions of the bone marrow: histopathology and microanalysis

1984

View full text Add to dashboard Cite

Silica deposition and characteristic nodular silicotic lesions of the bone marrow, virtually unknown features of silicosis, are described in a case of severe lung silicosis with silicotic granulomas of the liver and spleen. Scanning electron microscopy and X-ray microanalysis confirmed the presence of quartz and feld-spars. The bone marrow lesions included inconspicuous accumulations of silica-containing macrophages, free silica, slight lymphocyte and plasma cell infiltration, and reticulin fibre formation; and development of slightly larger partly fibrous silicotic nodules, comparable to those of the lung, liver, and spleen. Silicosis must therefore be considered in the differential diagnosis of bone marrow granulomas.

show abstract

Portlandzement [MAK Value Documentation in German language, 1993]

2012

The MAK‐Collection for Occupational Health and Safety

View full text Add to dashboard Cite

Veröffentlicht in der Reihe Gesundheitsschädliche Arbeitsstoffe , 19. Lieferung, Ausgabe 1993 Der Artikel enthält folgende Kapitel: Zement Allgemeine Definition Zusammensetzung der Zemente Zementherstellung Allgemeines Portlandzementklinker Zementchemie Portlandzementklinker Anwendung des Zements Hydratationsreaktionen Betonherstellung Verwendung von Zementen im Bergbau Analytik des Zementstaubes Erfahrungen beim Menschen Epidemiologische Querschnittsstudien Epidemiologische Längsschnittsstudien Erkenntnisse aus histologischen Untersuchungen Mortalitäts‐ und Morbiditätsstudien zur Frage der kanzerogenen Wirkung Tierexperimentelle Untersuchungen Inhalative Applikation Intratracheale Applikation Intraperitoneale Applikation Orale Applikation Begründung des MAK‐Wertes

show abstract

Pneumonokoniose durch Zementstaub

Cited by 19 publications

References 7 publications

Pulmonary and hepatic granulomatous disorders due to the inhalation of cement and mica dusts.

Pulmonary and hepatic granulomatous disorders due to the inhalation of cement and mica dusts.

Silicotic lesions of the bone marrow: histopathology and microanalysis

Portlandzement [MAK Value Documentation in German language, 1993]

Contact Info

Product

Resources

About