“…Administrative data are often used for population-level assessments of utilization of care or expenditures, especially for conditions with low prevalence. For example, U.S. insurance claims databases, both Medicaid and private insurance, have been used to estimate medical costs, 2,3,32,33 uptake of antibiotic prophylaxis, 19,26,28,31,34,48 documented receipt of immunizations, 31,34,47,57 use of hydroxyurea, 35,37,55,[58][59][60][61][62][63] and receipt of transcranial doppler (TCD) screening among individuals with SCD. 27,31,38,46,47,[64][65][66] Some of those studies, especially ones published in the past 5 years, merged NBS or clinical databases, which were used to identify cases of SCD, with linked claims data that were used to track utilization of services.…”