“…These complications may be infectious, such as orbit or facial cellulites, or destructive in nature, with the ulceration of the posterior pharyngeal wall, septal perforation with saddle nose, palatal perforation (16,305), and, in extreme cases, penetration into the central nervous system, with meningitis, pneumocephalus (193), or death, with a fatality rate of up to 1.19% (305). The invasion of the sinus cavities may impose a differential diagnosis of sinusitis.…”