Pneumatocele formation in a patient with Proteus mirabilis pneumonia

Lysy, Joseph; Werczberger, A.; Globus, Morton; Chowers, Itay

doi:10.1136/pgmj.61.713.255

Cited by 13 publications

(12 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The high frequency of P. mirabilis recovery from chicken livers (Table 2) is alarming, due to the documented literature of the involvement of this organism in different human conditions including pneumonia, 8,10 septicemia, central nervous system infection, 11 food poisoning, 32,33 and urolithiasis. 12 In addition, P. mirabilis is a proteolytic bacterium that is proven lately to alter the pathogenicity of avian influenza viruses, due to its ability to cleave the hemagglutinin protein of this virus.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4][5] The most important poultry organisms causing zoonoses are Salmonella spp., 5 Campylobacter spp., 6 and avian influenza. 3,4 Proteus mirabilis has been reported as one of the causative agents of human pneumonia 7,8 and other lung infection conditions. 9 Proteus mirabilis causes 90% of Proteus infections and is mostly found in people with compromised immune system.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of phenotypic and virulence genes characteristics in human and chicken isolates ofProteus mirabilis

Barbour

Hajj²,

Hamadeh³

et al. 2012

Pathogens and Global Health

View full text Add to dashboard Cite

The objective of this work is to compare the phenotypic and virulence genes characteristics in human and chicken isolates of Proteus mirabilis. The bacterial examination of 50 livers of individual broilers, marketed by four major outlets, revealed a high recovery of P. mirabilis (66%), and a low recovery frequency of Salmonella spp. (4%), Serratia odorifera (2%), Citrobacter brakii (2%), and Providencia stuartii (2%). The phenotypic biochemical characterization of the recovered 33 chicken isolates of P. mirabilis were compared to 30 human isolates (23 urinary and six respiratory isolates). The comparison revealed significant differences in the presence of gelatinase enzyme (100% presence in chicken isolates versus 91.3 and 83.3% presence in human urinary and respiratory isolates, respectively, P,0.05). The H 2 S production occurred in 100% of chicken isolates versus 95.6 and 66.7% presence in human urinary and respiratory isolates, respectively, P,0.05). The other 17 biochemical characteristics did not differ significantly among the three groups of isolates (P.0.05). Two virulence genes, the mrpA and FliL, were having a typical 100% presence in randomly selected isolates of P. mirabilis recovered from chicken livers (N510) versus isolates recovered from urinary (N55) and respiratory specimens of humans (N55) (P.0.05). The average percentage similarity of mrpA gene nucleotide sequence of poultry isolates to human urinary and respiratory isolates was 93.2 and 97.5-%, respectively. The high similarity in phenotypic characteristics, associated with typical frequency of presence of two virulence genes, and high similarity in sequences of mrpA gene among poultry versus human P. mirabilis isolates justifies future investigations targeting the evaluation of adaptable pathogenicity of avian Proteus mirabilis isolates to mammalian hosts.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison of phenotypic and virulence genes characteristics in human and chicken isolates ofProteus mirabilis

Barbour

Hajj²,

Hamadeh³

et al. 2012

Pathogens and Global Health

View full text Add to dashboard Cite

show abstract

“…The occurrences of P. mirabilis pneumonia were sporadic and showed no evidence of outbreak in the hospital. In the literature, community-acquired pneumonia is reported in only one female patient aged 47 years who developed a pneumatocele [3], and the frequency of P. mirabilis becoming the causative organism of community-acquired pneumonia was considered as extremely low.…”

mentioning

confidence: 99%

Clinical features of Proteus mirabilis pneumonia

Okimoto

Hayashi

Ishiga

et al. 2010

Journal of Infection and Chemotherapy

View full text Add to dashboard Cite

“…In such instances, emergent decompression is indicated. There have been several case reports of percutaneous decompression of tension PC by needle aspiration, 11 catheter drainage, 4,32 or chest tube drainage 12 under CT or fluoroscopic guidance. Persistent air leak from bronchopleural fistula formation during mechanical ventilation is a serious complication of ventilator therapy leading to inefficient ventilation through increased dead space ventilation.…”

Section: Mechanical Ventilation In Pcsmentioning

confidence: 99%

Pneumatocele as a Complication of Bronchoscopy: A Case Report and Review of Literature

Raman

Mushlin

Awsare

2007

Journal of Bronchology

View full text Add to dashboard Cite

We report a case of pneumatocele (PC) caused by bronchoscopy and bronchoalveolar lavage performed in a patient with human immunodeficiency virus infection. We speculate that coughing during the bronchoscopy may have contributed to the pathophysiology. A PC is a gas-filled cystic cavity in the lung parenchyma and the mechanism of formation is a 1-way valve that only allows airflow into the cavity. PCs have been described as a congenital malformation, in necrotizing infections, in chronic obstructive pulmonary disease, in hydrocarbon ingestion with aspiration, in human immunodeficiency virus positive adults with Pneumocystis jiroveci pneumonia, and as a result of blunt thoracic trauma. These lesions frequently resolve spontaneously. Most investigators suggest that the treatment is conservative with close follow-up, and invasive approaches should be reserved for patients who develop complications. Features such as fever, cough, and tachypnea, more than 50% involvement of hemithorax, persistent atelectasis, presence of a bronchopleural fistula, and infection in a PC should prompt image-guided transthoracic aspiration and catheter drainage or surgery.

show abstract

Pneumatocele formation in a patient with Proteus mirabilis pneumonia

Cited by 13 publications

References 10 publications

Comparison of phenotypic and virulence genes characteristics in human and chicken isolates ofProteus mirabilis

Comparison of phenotypic and virulence genes characteristics in human and chicken isolates ofProteus mirabilis

Clinical features of Proteus mirabilis pneumonia

Pneumatocele as a Complication of Bronchoscopy: A Case Report and Review of Literature

Contact Info

Product

Resources

About