Pneumatic tube system transport and false hyperkalemia related to leukocytosis: a retrospective analysis

Grzych, Guillaume; Roland, Estelle; Lezier, Doriane; Beauvais, David; Maboudou, Patrice; Lippi, Giuseppe

doi:10.1684/abc.2019.1444

Cited by 2 publications

(1 citation statement)

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“…Firstly, patient characteristics may influence pre analytical phase such as feeding state [1] or gender [2]. Physiological changes could promote some pre analytical events such as cell lysis in the form of hemolysis [3,4] or leukocyte lysis that could be related to the type and levels of blood cells or even some hematological disorders [5][6][7]. Physiological changes could also modulate other measurements such as calcium influenced by internal pH and albumin concentrations that could complicate medical interpretation and diagnosis [8,9].…”

Section: Editoralmentioning

confidence: 99%

"The Rising Importance of Pre-Analytical Phase in Medical and Research Laboratory, A New Challenge in the Omics Era"

Grzych

2020

BJSTR

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Laboratory analysis involves three main phases: pre-analytical, analytical and post analytical. For a long time, analytical and post-analytical phases were deemed important in medical biology. However, in the last few years, there is growing awareness about pre analytical aspects and issues making it the new major challenge in medical laboratory. Pre analytical phase encompasses a large range of variables that are associated with patient characteristics, sample collection and sample processing. Pre analytical phase is of paramount importance in medical diagnostics, but it continues to be underestimated in research and clinical trials. A paradigm shift in the quality management of pre analytical phase is overdue, especially with the increase of clinical omics application such as metabolomics.

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