PMS60 Infliximab Therapy Improves the Quality of Life of Ankylosing Sporidylitis Patients in China

Abstract

Arthritis (RA) group with a clinical classification category of CCC 202. They were matched with an equal number of respondents without RA as controls in order to minimize the sample selection bias, using Greedy Match Propensity Score Matching. Pre-disposing, enabling and need variables were matched using Chi-square tests for categorical variables and t-tests for continuous variables in SAS, version 9. Health-related quality of life instruments used were the Physical Component Summary (PCS-12) and the Mental Component Summary (MCS-12) of the SF-12 Health Survey and the EuroQol 5D index. T-tests in STATA (R) were used to measures group differences. RESULTS: Patients were statiscally matched on nine of ten variables. The mean (SE) PCS-12 scores for the RA and Non-RA groups were 34.25 (1.03) and 45.46 (1.07). The mean (SE) MCS-12 scores for the RA and Non-RA groups were 47.50 (1.01) and 51.14 (0.83). The mean (SE) EQ-5D index scores for the RA and Non-RA groups were 0.74 (0.02) and 0.86 (0.01). All lower scores were significant at an a priori alpha value of 0.05. CONCLUSIONS: Lower scores on all measures indicate that non-institutionalized adults with self-reported Rheumatoid Arthritis (RA) have a significantly lower health-realated quality of life.