PLM-GAN: A Large-Scale Protein Loop Modeling Using pix2pix GAN
Mena Nagy A. Khalaf,
Taysir Hassan A Soliman,
Sara Salah Mohamed
Abstract:Revealing the tertiary structure of proteins holds huge significance as it unveils their vital properties and functions. These intricate three-dimensional configurations comprise diverse interactions including ionic, hydrophobic, and disulfide forces. In certain instances, these structures exhibit missing regions, necessitating the reconstruction of specific segments, thereby resulting in challenges in protein design, which encompasses loop modeling, circular permutation, and interface prediction. To address t… Show more
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