PLLA grafting draws GO from PGA phase to the interface in PLLA/PGA bone scaffold owing enhanced interfacial interaction

An electrical microenvironment constructed based on electromagnetic induction stimulates neural differentiation

“…Importantly, the OD value of the NH 2 -MXene/PLLA groups increased from 2.27 to 2.53 after applying the rotating MF, which proved that the NH 2 -MXene/PLLA conduit could better promote cell proliferation under a rotating MF. 52,53 Similarly, the cell viability test showed the NH 2 -MXene/PLLA group under a rotating MF had the best promoting impact on cell growth (Fig. 6c).…”

Structural and Functional Adaptive Artificial Bone: Materials, Fabrications, and Properties

“…However, limited by the laser spot size and the heat affected zone of laser sintering, it is also difficult for laser additive manufacturing technology to fabricate surface micro and nano scale pores. In our previous studies, [11,21,212] we have utilized the advantages of laser additive manufacturing technology to fabricate individualized 3D entities of artificial bone by layerby-layer stacking and free-forming. By controlling the spot size and scanning spacing to match, the preparation of hundreds of micrometer scale holes could be realized.…”

“…[18][19][20] Biopolymers, including poly (L-lactide) (PLLA) and poly (ε-caprolactone) (PCL), possess good biosafety, biodegradability, and formability, but their strength is insufficient, and their degradation products are acidic, easily resulting in aseptic inflammatory reaction. [21][22][23][24][25] Until now, a single kind of material is not sufficient to meet the properties requirements of bone scaffold.…”

Direct osteogenesis and immunomodulation dual function via sustained release of naringin from the polymer scaffold

“…21 The NG-MBG/PLLA scaffolds were fabricated using a custommade SLS system. [22][23][24] In a few words, the mixed powder was spread evenly on a laser sintering platform, and a laser beam was used to sinter the powder according to a pattern predetermined by the system. When sintering was complete, the platform was moved down, the powder was again placed flat on the platform, and laser melting was conducted.…”