Plexiform schwannomas of the sciatic nerve:a case report and review of the literature

Yan, Jing Jou; Zhou, Ruijun; Liu, Bingxin; Xu, Yuting; Chen, Bolai

doi:10.1016/j.heliyon.2023.e18020

Cited by 2 publications

(5 citation statements)

References 41 publications

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“…Magnetic resonance imaging (MRI) stands out as a powerful tool for diagnosing plexiform schwannoma, offering definitive insights. Schwannomas manifest in MRI as fusiform masses with tapered ends, displaying high intensity on T2-weighted images and low to moderate intensity on T1-weighted images [8]. Careful intracranial and spinal MRI is necessary to exclude potential neurofibromatosis type 2 (NF2) in young patients, as up to 5% of PS cases may be associated with NF2 [5][6][7][8].…”

Section: Discussionmentioning

confidence: 99%

“…Schwannomas manifest in MRI as fusiform masses with tapered ends, displaying high intensity on T2-weighted images and low to moderate intensity on T1-weighted images [8]. Careful intracranial and spinal MRI is necessary to exclude potential neurofibromatosis type 2 (NF2) in young patients, as up to 5% of PS cases may be associated with NF2 [5][6][7][8]. We were not able to get an MRI done as, in resource-limited settings, where MRI is often not feasible due to availability and economic constraints, excisional biopsy becomes a valuable alternative.…”

Section: Discussionmentioning

confidence: 99%

“…Histological examination, the diagnostic gold standard for tumors, revealed the distinctive composition of plexiform schwannomas. Microscopy highlighted Antoni A regions rich in spindle cells and Antoni B regions with loose mucoid stroma [8]. Buoyant S-100 protein immunostaining aids in diagnosing plexiform schwannomas, neurofibroma, and malignant peripheral nerve sheath tumors [9].…”

Section: Discussionmentioning

confidence: 99%

“…Patients who fail medical attention may seek care only after experiencing sudden changes in the lesion, such as excessive growth, abnormal bleeding, or pain. Although rare, long-standing cases of schwannoma may transform into malignant tumors [8].…”

Section: Discussionmentioning

confidence: 99%

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Giant Plexiform Schwannoma on the Medial Aspect of the Left Thigh

Kumar,

Singh,

Singh

et al. 2023

Cureus

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Plexiform schwannoma (PS), or neurilemmoma, is an uncommon benign tumor originating from a peripheral nerve sheath. It consists of Schwann cells organized in an intricate, web-like pattern. A male farmer in his 50s from rural India sought medical attention for a painless mass on his left thigh, present for 30 years. Physical examination revealed a firm, non-tender mass with restricted mobility. Imaging, including X-ray and ultrasound, indicated a neoplastic lesion. Fine needle aspiration (FNA) cytology revealed spindle-shaped cells, prompting a provisional diagnosis of a spindle cell lesion. Surgical excision was performed successfully, with histopathological examination confirming PS. He experienced no postoperative complications, and at the one-year follow-up, the complete resolution of symptoms and normal daily activities were observed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Giant Plexiform Schwannoma on the Medial Aspect of the Left Thigh

Kumar,

Singh,

Singh

et al. 2023

Cureus

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“…However, compression neuropathies can represent the initial presentation of other PND forms, like genetic or systemic [ 11 ]. Nerve tumors, like schwannoma and neurofibroma, can be particularly impactful and can cause severe sensory and/or motor symptoms; they belong to the category of mononeuropathies, even if the involvement may be in multiple nerves in genetic conditions [ 12 ]. A particular category of mononeuropathies includes traumatic nerve injuries [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Rehabilitation of Peripheral Neuropathies: From Lexical Analysis of the Literature to Identification of Clinical Protocols

Coraci,

Romano,

Ragazzo

et al. 2023

JCM

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Peripheral nervous system diseases are a complex and heterogenous group of diseases affecting the different nerves with various severity and impact on quality of life. The current literature does not provide a structured guide for the rehabilitation of these conditions. We performed a lexical literature evaluation based on graph theory to clarify this topic. We performed a search on PubMed and calculated the frequencies of the words indicating rehabilitation approaches, nerves, and diseases. We found the usefulness of exercises and different physical agents, like laser and ultrasound therapy and neuromuscular stimulation vibration therapy. Orthoses are useful for entrapment, trauma, and hereditary diseases. Correct knowledge and assessment of the neuropathies are fundamental for the therapeutic decision and to guide rehabilitation. Despite the usefulness shown by the different approaches to modulating pain, improving muscle strength and endurance, and ameliorating balance and the sensory system, further studies are needed to define the best-personalized protocols.

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Plexiform schwannomas of the sciatic nerve:a case report and review of the literature

Cited by 2 publications

References 41 publications

Giant Plexiform Schwannoma on the Medial Aspect of the Left Thigh

Giant Plexiform Schwannoma on the Medial Aspect of the Left Thigh

Rehabilitation of Peripheral Neuropathies: From Lexical Analysis of the Literature to Identification of Clinical Protocols

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