Pleurodesis for spontaneous pneumothorax

Ofoegbu, Reginald O.

doi:10.1016/0002-9610(80)90057-4

Cited by 11 publications

(2 citation statements)

References 18 publications

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“…iodofo rm o r sterile olive oil to insti ll into the pleural cavity . with app arently good results ( 13). Scar ify ing agents seem to have benefits.…”

Section: Discussionmentioning

confidence: 99%

Surgical Management of Spontaneous Pneumothorax

Brande¹,

Staelens²,

Cham³

et al. 1984

Thorac cardiovasc Surg

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Spontaneous pneumothorax is a common surgical problem. Although the general principles of drainage of the pleural space and of prevention of recurrence seem well known, the literature shows differences in success rates concerning the treatment of a first pneumothorax and of the eventual recurrences. This is probably due to some technical factors and different views on the therapeutical strategy. In this retrospective review of 62 patients with spontaneous pneumothorax, 8 were treated by bed rest for their not enlarging and less than 20% pneumothorax, and 54 were treated by closed chest tube thoracostomy with an early success rate of 93.5% at the first admission. The simultaneous use of scarifying agents and closed chest drainage appears useful for the treatment of immediate or first recurrence. Sixteen patients were readmitted later for ipsilateral recurrence. According to the magnitude of their pneumothorax, they were treated by bed rest or tube thoracostomy with scarifying agents. Four of these patients needed thoracotomy with oversuturing of subpleural blebs and pleurodesis. The total thoracotomy rate of the initial patient population was 12.9% after an average follow up period of 24.8 months.

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“…iodofo rm o r sterile olive oil to insti ll into the pleural cavity . with app arently good results ( 13). Scar ify ing agents seem to have benefits.…”

Section: Discussionmentioning

confidence: 99%

Surgical Management of Spontaneous Pneumothorax

Brande¹,

Staelens²,

Cham³

et al. 1984

Thorac cardiovasc Surg

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“…However, it is expensive compared to other agents thus limiting its use. Dextrose 50%, transforming growth factor beta (TGF-b), doxycycline, olive oil, minocycline, corynebacterium parvum extract, interferons (α and β), interleukins (IL-2) and several chemotherapeutic agents such as cisplastin, cytosine arabinoside and mitoxantrone have been used, though with variable efficacy rates [ 10 , 21 - 23 ]. In Nigeria the burden of malignant pleural effusion is huge and similar to what obtains in other developing countries.…”

Section: Introductionmentioning

confidence: 99%

Pleurodesis with povidone iodine in patients with malignant pleural effusion in a tertiary center in Nigeria

Omoregbee

Okugbo

2021

Pan Afr Med J

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Introduction malignant pleural effusion occurs as a consequence of a primary or metastatic malignant process involving the pleura. The aim of pleurodesis is to prevent re-accumulation of the effusion and avoid the need for repeated hospitalization. Povidone iodine has been used in other climes for pleurodesis with good results. The aim of this study is to assess the efficacy and safety of povidone iodine in producing pleurodesis as compared to tetracycline. Methods the study is a prospective experimental study. The patients are randomized into two groups A (tetracycline-control) and B (povidone iodine). All patients are assessed with chest X-ray after 1 week and 1 month. The responses were ascribed as complete, partial or failure. Results thirty patients were recruited into this study, 15 patients in each group A (tetracycline) and B (povidone iodine). The mean age was 45.7±14.24 years. The commonest primary malignancy was Breast cancer (70%) followed by bronchogenic cancer (10%). Seventy three (73%) of the patients in this study had complete response and in 7% pleurodesis failed whilst 20% has partial response. In the povidone group the success rate was 93.4% and in the tetracycline group was 93.3% with a p-value of 0.716. There was no statistical difference in the responses based on the agents used. Conclusion malignant pleural effusion is a devastating condition as it heralds the end-of-life processes of a primary malignancy. Povidone iodine is a safe, cheap, effective, widely available and effective pleurodesing agent for use in patients with malignant pleural effusion.

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