Pleural nodular mesothelial/histiocytic hyperplasia associated with syphilis

Berg, Kyra B.; Liebling, Peter D.; Kubik, Melanie J.; Attanoos, Richard; Galateau-Sallé, Françoise; Roggli, Victor L.; Wick, Mark R.; Churg, Andrew

doi:10.1016/j.ehpc.2018.03.005

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2022

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“…Consequently, ILH may be ontogenically and pathogenetically different from non-ILH HNR. The former being a monocyte-derived condition driven by immune activation, whereas the latter being the expression of a mechanism of host defense of resident macrophages driven by mesothelial inflammation (eg, in cases associated with endometriosis or neoplasm) or infection (11).…”

Section: Discussionmentioning

confidence: 99%

Intralymphatic Histiocytosis Associated With Tubo-ovarian High-grade Serous Carcinoma: Case Report and Review of the Literature

Bonometti

Carbone

Cassani

et al. 2022

International Journal of Gynecological Pathology

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Intralymphatic histiocytosis is a condition characterized by the accumulation of mononuclear phagocytes within lymphatic vessels and lymph nodes that may be isolated or secondary to autoimmune or neoplastic diseases. Secondary intralymphatic histiocytosis frequently involves the skin and is associated with malignancies in up to a tenth of cases. We describe a case of intralymphatic histiocytosis associated with high-grade serous carcinoma and reviewed the literature on neoplasia associated with the broader category of histiocytoses with raisinoid nuclei. Moreover, we try to elucidate the pathogenesis of these rare and intriguing disorders.

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Section: Discussionmentioning

confidence: 99%