Pleural calcification as a sign of asbestosis

Lawson, Jack

doi:10.1016/s0009-9260(63)80030-6

Cited by 19 publications

(1 citation statement)

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“…The results support the causal relationship between hyaline parietal pleural plaques and exposure to asbestos based on radiological examinations during life, and on necropsy findings (Kiviluoto, 1960;Lawson, 1963;Meurmann, 1966;Anton, 1967 and. Plaques were found in 41 of 334 necropsies (12 3 %) which is close to the findings at the London Hospital (11-2 % of 134 necropsies) .…”

Section: Discussionsupporting

confidence: 82%

The pathology of parietal pleural plaques

1971

J Clin Pathol

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sYNoPsis The incidence, morbid anatomy, histology, and relationship of hyaline pleural plaques to exposure to asbestos has been studied.Plaques were found in 12-3 % of 334 hospital necropsies (in an urban population in Glasgow, 41 cases). In 85-3 % (35 cases) asbestos bodies were found in the lungs. There is evidence of a doseresponse relationship between the number of asbestos bodies found in the lungs and the presence of pleural plaques.The selective distribution of plaques within the pleural cavities suggests that mechanical factors play a part in their localization.Histological examination contributed little to understanding the mechanism of plaque formation; that asbestos bodies have been detected in only a few cases suggest that their presence in the parietal pleura is not essential to plaque formation. The suggested mechanisms of plaque formation are discussed.In the earlier literature on asbestosis there is reference to changes in pleural cavities (

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Section: Discussionsupporting

confidence: 82%