(Plenary) Printed Electrochemical Instruments for Biosensors

Abstract

Mobile diagnostics for healthcare, food safety and environmental monitoring, demand a new generation of inexpensive sensing systems suitable for production in high volume. Herein we report on the development of a new disposable electrochemical instrument exploiting the latest advances in printed electronics and printed biosensors. The current system is manufactured under ambient conditions with all interconnections printed; electrochemical measurements and data elaboration are realized by the integration onto the platform of two chips: a MICROCHIP-PIC24F16KA101 and a Texas Instrument’s LMP91000. A PEDOT.PSS vertical electrochromic display (VECD) is also incorporated into the system to visualize the data. A printed Enfucell 3V manganese dioxide battery was used to deliver the required power. Finally, in order to demonstrate the utility of the system, screen-printed sensors for the detection of glucose were added and the performance of the overall system was evaluated.

Calorimetric Biosensing System for Quantification of Urinary Creatinine

“…No matter the economy of scale, these devices are eventually not so inexpensive especially when compared to screen printed enzyme electrodes used in electrochemical glucose and other biosensors. 8 Therefore, the development of a robust microcalorimeter with disposable fluidics containing the recognition element is of immense interest. Acute kidney injury (AKI) occurs in 5−7% of hospitalized patients 9 and results in a mortality rate of about 50%, 10 while chronic kidney disease (CKD) has also become a significant global health problem, with prevalence rates in the United States of 13%.…”