Platynosomum concinnum infection in cats in Nigeria

Bo, Ikede; Gj, Losos; Tt, Isoun

doi:10.1136/vr.89.24.635

Cited by 9 publications

(2 citation statements)

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“…The microscopic liver injuries described, ranging from mild to severe, are similar to commonly reported findings (IKEDE et al, 1971;RETNASABAPATHY & PRATHAP, 1971;FERREIRA et al, 1999;HEADLEY et al, 2012). Histopathological comparison is difficult, since stray cats used during this study had no known medical history, and possibly with natural infections which could be ongoing for different period of times.…”

Section: Discussionsupporting

confidence: 84%

Feline platynosomiasis: analysis of the association of infection levels with pathological and biochemical findings

Ramos

Santos

Freitas

et al. 2017

Rev. Bras. Parasitol. Vet.

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Platynosomiasis is a common feline hepatic disease caused by Platynosomum fastosum (Trematoda -Dicrocoelidae), which is also known as 'lizard poisoning'. Most reports of feline platynosomiasis show that this disease is sporadic and manifests with uncommon lesions; its pathogenicity is still not well understood. This study aimed to describe liver injuries and enzymatic changes associated with natural P. fastosum infection in 47 stray cats in an endemic area. Overall, 38.3% (18/47) of cats were parasitized, and 2,358 flukes (P. fastosum) were collected (131 -mean intensity of parasitism; 50.2 -mean abundance). The alanine transaminase (ALT) measure was significantly higher in parasitized animals, while alkaline phosphatase (ALP) showed no statistical difference between parasitized and non-parasitized animals. In infected animals, gross pathological lesions and microscopic liver injuries ranged from mild to severe, and were similar to those in previous descriptions of feline platynosomiasis. Nonetheless, the intensity of parasitism was not related to the severity of macroscopic or microscopic hepatic injuries. However, feline platynosomiasis should be considered in the differential diagnosis of feline liver disorders, as well as, in any program of helminth control, even if no clinical abnormalities are present.Keywords: Platynosomum fastosum, liver, lesions, ALT, ALP. ResumoPlatinossomiase é uma doença hepática felina comum causada por Platynosomum fastosum (Trematoda -Dicrocoelidae), também é conhecida como "envenenamento por lagartixa". A maioria dos relatos de platinossomiase felina mostra que esta doença é esporádica e se manifesta com lesões incomuns; sua patogenicidade ainda não é bem compreendida. Este estudo objetivou descrever as lesões no fígado e alterações enzimáticas associadas à infecção natural por P. fastosum em 47 gatos errantes em uma área endêmica. No total, 38,3% (18/47) dos gatos estavam parasitados, e 2.358 trematódeos (P. fastosum) foram coletados (131 -intensidade média de parasitismo; 50,2 -abundância média). A quantidade de alanina transaminase (ALT) foi significativamente maior nos animais parasitados, enquanto a fosfatase alcalina (ALP) não apresentou diferença estatística entre os animais parasitados e não parasitados. Nos animais infectados, lesões patológicas macroscópicas e microscópicas hepáticas variaram de leve a grave, e foram semelhantes a descrições anteriores de platinossomiase felina. No entanto, a intensidade do parasitismo não foi relacionada à gravidade das lesões hepáticas macroscópicas ou microscópicas. Contudo, a platinossomiase felina deve ser considerada no diagnóstico diferencial de distúrbios hepáticos em felinos, assim como, em qualquer programa de controle de helmintos, mesmo que nenhuma anormalidade clínica esteja presente.

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Section: Discussionsupporting

confidence: 84%

Feline platynosomiasis: analysis of the association of infection levels with pathological and biochemical findings

Ramos

Santos

Freitas

et al. 2017

Rev. Bras. Parasitol. Vet.

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“…The most common histopathological findings include diffuse portal congestion, hepatic sinusoid dilation, hepatocyte degeneration, mild centrolobular fatty change that may involve the whole lobule, polymorphonuclear inflammatory infiltrate and an abundant collection of mononuclear cells around biliary ducts (Ferreira et al 1999, Ferreira andAlmeida 2003). Hyperplasia of the biliary duct epithelium, periductal inflammation and fibrosis, are also observed, and may lead to obstructive disorders or terminal liver disease (Ikede et al 1971, Center 1996, Ferreira et al 1999. Bile duct distension increases with growth of adult flukes (Bielsa andGreiner 1985, Center 1996).…”

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confidence: 99%

Cystic liver disease related to high Platynosomum fastosum infection in a domestic cat

Xavier

Morato

Righi

et al. 2007

Journal of Feline Medicine and Surgery

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Platynosomum fastosum is a small fluke found in the biliary ducts and gallbladder of cats. Its lifecycle includes the snail Sublima octona as intermediate host, and lizards, toads and geckos as paratenic hosts. Affected cats are usually adult and acquire the parasite by feeding on infected lizards. This parasite occurs across the world but is more frequent in tropical areas. The clinical signs range from none to obstruction of the biliary tract, with hepatic failure and death, reinforcing the necessity of including the liver fluke Platynosomum fastosum in the differential diagnosis of hepatic diseases in cats. This report describes an unusual case of a cat with a polycystic hepatic disease and a severe infestation by Platynosomum fastosum and presents a review of the literature.

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Parasites of Cats

Bowman

Baker

2007

Flynn's Parasites of Laboratory Animals

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Platynosomum concinnum infection in cats in Nigeria

Cited by 9 publications

References 0 publications

Feline platynosomiasis: analysis of the association of infection levels with pathological and biochemical findings

Feline platynosomiasis: analysis of the association of infection levels with pathological and biochemical findings

Cystic liver disease related to high Platynosomum fastosum infection in a domestic cat

Parasites of Cats

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