Plato's Versuche über die Herstellung und Verwendung von ”Trichophytin„

Neisser, A.

doi:10.1007/bf01986861

Cited by 30 publications

(10 citation statements)

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“…Studies on hypersensitivity in dermatophytosis started in 1902 when Neisser published the work of his late assistant Plato on the preparation and usefulness of "trichophytins" (173). Plato grew Trichophyton species isolated from patients with deep-seated trichophytosis in a liquid medium consisting of beef extract, peptone, and maltose.…”

Section: Trichophyton Gypseummentioning

confidence: 99%

Immunology of dermatophytes and dermatophytosis.

Grappel¹,

Bishop²,

Blank³

1974

Bacteriological Reviews

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Section: Trichophyton Gypseummentioning

confidence: 99%

Immunology of dermatophytes and dermatophytosis.

Grappel¹,

Bishop²,

Blank³

1974

Bacteriological Reviews

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“…Activation of the host's defenses with killed whole mycelium or crude mycelial extracts injected intradermally or subcutaneously, the routes most useful for inducing cellmediated hypersensitivity (Chase, 1976), has had some success in clearing resistant infections in man. However, intradermal injections of "trichophytins" prepared from culture filtrates have had little effect on the course of infection (Neisser, 1902;Truffi, 1904;Traub and Tolmach, 1935).…”

Section: For Treatmentmentioning

confidence: 98%

“…The first studies on cutaneous hypersensitivity in dermatophytosis were carried out by Plato in 1902 (Neisser, 1902). The antigen that he prepared was a crude extract of mycelia of Trichophyton species which he called' 'trichophytin."…”

Section: Factors Contributing To Induction Of Inflammationmentioning

confidence: 99%

Immunology of Surface Fungi Dermatophytes

Grappel

1981

Immunology of Human Infection

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“…This period of search for fungi in various diseases of unknown etiology was followed by an other period that focussed its interest on tlie biological processes taking place in the course of mycotic infections. There are the dermatologists of the Breslau school (NEISSER 1902). Plato was the first to prove that injection of a fungus product (trichophytin) into the skin provokes a cutaneous reaction.…”

Section: Zusammenfassungmentioning

confidence: 99%

The Influence of Dermatology on the Development of Medical Mycology

Götz

2009

Mycoses

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Summary Even though all medical disciplines and related professions are nowadays interested in medical mycology, the historical approach reveals that dermatology is ‐ and always has been ‐ the pacemaker for this specific branch of research. After modern dermatology had been systematized and established in the 19th century, it attracted men such as Schönlein (1839), Gruby, and ‐ in the first place ‐ Sabouraud, the actual founder of medical mycology. The period of morphological studies was followed by a phase concerned with investigation into immunobiological processes in mycotic infections; this phase, too, was initiated by dermatologists. Closer cooperation in all disciplines of human and veterinary medicine, including biologists, botanists, and chemists, promises further progress in the studies of mycoses. Résumé Aujourd'hui toutes les branches médicales et les professions apparentées s'intéressent à la mycologie. Mais on peut considérer que la dermatologie reste‐ et a toujours été ‐ le pionnier dans le domaine de cette recherche spécifique. La systématisation des maladies cutanées et la création de la dermatologie moderne au XIXiEme siècle fut dominee par SCHÖNLEIN (1839) par Gruby, mais surtout par Sabouraud, le vrai fondateur de la mycologie medicale. L'étude de la morphologie fut suivie d'une phase d'investigation immunobiologique des affections mycosiques et une fois de plus, ce fut les dermatologues qui en prirent L'initiative. Aujourd'hui encore, on peut réaliser des faits nou‐veaux en mycologie par une étroite coopération des medicins, des vétérinaires, des botanistes, des biologistes, et des chimistes. Zusammenfassung Wenn auch heme an der Medizinischen Mykologie alle Disziplinen der Medizin und ver‐wandte Berufe interessiert sind, so hebt eine historische Betrachtung doch die Dermatologie als Schrittmacher für diesen Spezialforschungszweig besonders hervor. Über die Systembildung und Begründung der modernen Dermatologie im 19. Jahrhundert fuhrt der Weg zu Schönlein (1839), vor allem aber zu Gruby und Sabouraud, den eigentlichen Begründern der Medizinischen Mykologie. Der Periode der Morphologie folgte eine Phase, die sich der Erforschung der immunobiologischen Vorgänge bei Pilzaffektionen widmete. Auch diese ging primär von Dermatologen aus. Weitere Fortschritte bei der Erforschung der Pilzkrankheiten sind durch eine engere Zusammenarbeit aller Disziplinen der Human‐ und Veterinarmedizin, der Biologen, Botaniker und Chemiker zu erwarten. only cursory glance at its development, it becomes obyious that here dermatology plays a special role. Dermatology could briefly be defined as “the study of the skin and the visible mucous membranes”. Even before our days, changes in the aspect of the skin used to attract the attention of fellow men, especially of those who acted as priests and doctors of their tribes and races. The clinically obvious symptoms of a favus of the head, or a profound trichophytosis of the beard, or‐ clear‐cut ring‐ or bow‐shaped formations on the skin could hardly be overlooked by anybody...

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Plato's Versuche über die Herstellung und Verwendung von ”Trichophytin„

Cited by 30 publications

References 0 publications

Immunology of dermatophytes and dermatophytosis.

Immunology of dermatophytes and dermatophytosis.

Immunology of Surface Fungi Dermatophytes

The Influence of Dermatology on the Development of Medical Mycology

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