Platinum(II) and Copper(II) complexes of asymmetric halogen-substituted [NNʹO] ligands: Synthesis, characterization, structural investigations and antiproliferative activity

Rudbari, Hadi Amiri; Saadati, Arezoo; Aryaeifar, Mahnaz; Blacque, Olivier; Cuevas-Vicario, José Vicente; Cabral, Rui; Raposo, Luís R.; Fernandes, Alexandra R.

doi:10.1016/j.bioorg.2021.105556

Cited by 6 publications

(15 citation statements)

References 71 publications

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“…As shown in Fig. 3, for various substituents, the energies of 3 MC states and MECP are similar, and the values are 68.49, 70.69, 68.75 and 70.97 kcal mol À1 , respectively. It is indicated that the energies of 3 MC states and MECP for monometallic Pt(II) complexes may rely on the bond strength of Pt-X (X = heteroatom) coordinate bonds.…”

Section: 2mentioning

confidence: 65%

“…1, T planar 1 and T bent 1 possess obviously different geometric characters, i.e., the spin densities are located on the main ligand and the acac ligand (auxiliary ligand), respectively. Hence, they can be classified as 3 ILCT-acac (intraligand charge transfer) and 3 ILCT-main ligands. Since the electron transition character is closely related to the structural change during the transition process 41 Besides, different main group substituents are also taken into account, and the computed results are exhibited in Fig.…”

Section: Optimized Geometries Of Different T 1 States and The Corresp...mentioning

confidence: 99%

“…The relative energies of T 1 states, TS, 3 MC and MECP for monometallic Pt(II) complexes With the purpose of exploring the temperature-dependent nonradiative decay processes, i.e., T 1 -TS -3 MC -MECP, the corresponding geometries are optimized or calculated. The potential energy profiles of the deactivation pathways constructed using these geometries are shown in Fig.…”

Section: 2mentioning

confidence: 99%

“…In the application of anticancer drugs, previous studies report that some derivatives have been conjugated to Pt(II) drugs to elicit promising anticancer effects. [1][2][3][4][5][6] The oxaliplatin scaffold was chosen based on the findings that tetracarboxylato Pt(IV) compounds are generally stable toward reduction. 7,8 This prodrug supposedly exists in its intact Pt(IV) form in the dark but is activated to release oxaliplatin and PPA under the irradiation of red light.…”

Section: Introductionmentioning

confidence: 99%

“…Fig.8Schematic potential energy profiles of the deactivation pathways for 2Pt-1, 2Pt-2 and 2Pt-3, respectively 3. ES refers to the T 1 excited state.…”

mentioning

confidence: 99%

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Theoretical investigation of triplet potential energy surfaces for (C^C*) cyclometalated platinum(ii) complexes and the corresponding control strategies

et al. 2022

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Section: 2mentioning

confidence: 65%

Section: Optimized Geometries Of Different T 1 States and The Corresp...mentioning

confidence: 99%

Section: 2mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Fig.8Schematic potential energy profiles of the deactivation pathways for 2Pt-1, 2Pt-2 and 2Pt-3, respectively 3. ES refers to the T 1 excited state.…”

mentioning

confidence: 99%

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Theoretical investigation of triplet potential energy surfaces for (C^C*) cyclometalated platinum(ii) complexes and the corresponding control strategies

et al. 2022

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Complexation-induced nanoarchitectonics of sulfonate cailx[4]resorcinol substituted at the upper rim by N-methyl-d-glucamine fragments: Morphological transition and in vitro anticancer activity

Kashapova

Kashapov

Ziganshinа

et al. 2022

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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From Achiral Precursors to Copper Helical Coordination Polymers: Magnetic Properties and Electronic Structure

Rubio-Sepúlveda,

Huechucura,

Cruz

et al. 2024

Crystal Growth & Design

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We introduce two novel one-dimensional coordination polymers (CPs) with helical arrangements based on copper-(II) and an achiral Schiff base ligand, [Cu(L)(DMF)(X)] n (X = NO 3 − (1) and Cl − (2)), where L = 2-{[(pyridin-3-yl)imino]-methyl}phenol. Both structures crystallize in an orthorhombic unit cell with a P2 1 2 1 2 1 space group. In both compounds, unconventional noncovalent interactions are fundamental for the structural features, modulating the dihedral angle ca. 70°between the two aromatic rings that are part of the organic ligand. Magnetic measurements indicate that weak antiferromagnetic interactions predominate in both CPs, with a J value of −3.34 cm −1 for 1 and −4.95 cm −1 for 2, corroborated by ab initio first-principles calculations. Furthermore, electronic structure analyses reveal a semiconductor behavior for both CPs. First-principles calculations predict small polaron localization around the Cu sites, with a higher formation of electron polarons in compound 1 than in 2.

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Platinum(II) and Copper(II) complexes of asymmetric halogen-substituted [NNʹO] ligands: Synthesis, characterization, structural investigations and antiproliferative activity

Cited by 6 publications

References 71 publications

Theoretical investigation of triplet potential energy surfaces for (C^C*) cyclometalated platinum(ii) complexes and the corresponding control strategies

Theoretical investigation of triplet potential energy surfaces for (C^C*) cyclometalated platinum(ii) complexes and the corresponding control strategies

Complexation-induced nanoarchitectonics of sulfonate cailx[4]resorcinol substituted at the upper rim by N-methyl-d-glucamine fragments: Morphological transition and in vitro anticancer activity

From Achiral Precursors to Copper Helical Coordination Polymers: Magnetic Properties and Electronic Structure

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