Platinum decorated carbon nanotubes for highly sensitive amperometric glucose sensing

Abstract

Fine platinum nanoparticles (1–5 nm in diameter) were deposited on functionalized multi-walled carbon nanotubes (MWNTs) through a decoration technique. A novel type of enzymatic Pt/MWNTs paste-based mediated glucose sensor was fabricated. Electrochemical measurements revealed a significantly improved sensitivity (around 52.7 µA mM−1 cm−2) for glucose sensing without using any picoampere booster or Faraday cage. In addition, the calibration curve exhibited a good linearity in the range of 1–28 mM of glucose concentration. Transmission electron microscopy (TEM) and x-ray photoelectron spectroscopy (XPS) were performed to investigate the nanoscale structure and the chemical bonding information of the Pt/MWNTs paste-based sensing material, respectively. The improved sensitivity of this novel glucose sensor could be ascribed to its higher electroactive surface area, enhanced electron transfer, efficient enzyme immobilization, unique interaction in nanoscale and a synergistic effect on the current signal from possible multi-redox reactions.

Mediator-free interaction of glucose oxidase, as model enzyme for immobilization, with Al-doped and undoped ZnO thin films laser-deposited on polycarbonate supports

“…It may be inferred that GOx immobilized electrodes does not have interference from the fact that its operation condition is negative potential. The potential used in this study is lower compared to previously reported potentials for sensing in mediated and non-mediated biosensors [44,45]. Since the present study contemplated devising a low cost electrode on an inexpensive substrate PC, only one-time usage was envisaged.…”

Electrochemical Functionalization of InP Porous Nanostructures with a GOD Membrane for Amperometric Glucose Sensors

“…We obtained 0.1 M phosphate buffer solutions ͑PBSs͒ with pH 7.0 and 7.4 from Nacalai Tesque Inc. and used them as solvents for the electrodeposition of GOD and for electrochemical measurements, respectively. We obtained 60% HNO 3 and 35% HCl solutions from Kishida Chemical Inc. and used them as electrolytes for the formation of porous structures, as described in the literature. 26 All other solvents and reagents used were of analytical grade, and deionized ͑DI͒ water was used to prepare the solutions.…”

“…Xie et al reported that a higher sensitivity of 52.7 A/mM cm 2 was obtained for Pt-coated multiwalled carbon nanotube electrodes. 3 Improved sensitivity of the InP porous electrodes can be possibly obtained by optimizing such structural properties as pore depth and pore diameter and by using Pt nanoparticles to enhance functionalization inside the pores.…”

Elimination of Influence by Interference Substance on Amperometric Enzyme Biosensor Response Using Wavelet Transformation

“…22 Firstly, we discuss the availability of WT for elimination of interfering substances by using simulated sigmoidal waves. Simulated sigmoidal waves were prepared by a Gompertz function using Microsoft Excel.…”