Platinum‐Catalyzed Intermolecular Hydroamination of Alkenes: Halide‐Anion‐Promoted Catalysis

Brunet, Jean‐Jacques; Chu, Ngoc‐Chau; Rodriguez‐Zubiri, Mireia

doi:10.1002/chin.200752263

Cited by 1 publication

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“…At this point, besides the traditional alkylation methods to get amines, 43 the development of improved catalytic processes for the synthesis of amines is still an active topic of research. For example, during the past decade, various catalytic aminations, such as palladium-and copper-catalyzed aminations of aryl halides, 44,45 hydroaminations, 46,47 hydroaminomethylations, 48 or reductive aminations 49,50 have received increased attention due to the high levels of conversion and yields of the corresponding amines. However, a re-examination of the above processes from an environmental point of view (utilization of hazardous chemicals and solvents) shows that BH processes are definitely superior.…”

Section: Introductionmentioning

confidence: 99%

Advances in One-Pot Synthesis through Borrowing Hydrogen Catalysis

2018

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The borrowing hydrogen (BH) principle, also called hydrogen auto-transfer, is a powerful approach which combines transfer hydrogenation (avoiding the direct use of molecular hydrogen) with one or more intermediate reactions to synthesize more complex molecules without the need for tedious separation or isolation processes. The strategy which usually relies on three steps, (i) dehydrogenation, (ii) intermediate reaction, and (iii) hydrogenation, is an excellent and well-recognized process from the synthetic, economic, and environmental point of view. In this context, the objective of the present review is to give a global overview on the topic starting from those contributions published prior to the emergence of the BH concept to the most recent and current research under the term of BH catalysis. Two main subareas of the topic (homogeneous and heterogeneous catalysis) have been identified, from which three subheadings based on the source of the electrophile (alkanes, alcohols, and amines) have been considered. Then the type of bond being formed (carbon-carbon and carbon heteroatom) has been taken into account to end-up with the intermediate reaction working in tandem with the metal-catalyzed hydrogenation/dehydrogenation step. The review has been completed with the more recent advances in asymmetric catalysis using the BH strategy.

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