Platform construction and extraction mechanism study of magnetic mixed hemimicelles solid-phase extraction

Abstract

Simple, accurate and high-throughput pretreatment method would facilitate large-scale studies of trace analysis in complex samples. Magnetic mixed hemimicelles solid-phase extraction has the power to become a key pretreatment method in biological, environmental and clinical research. However, lacking of experimental predictability and unsharpness of extraction mechanism limit the development of this promising method. Herein, this work tries to establish theoretical-based experimental designs for extraction of trace analytes from complex samples using magnetic mixed hemimicelles solid-phase extraction. We selected three categories and six sub-types of compounds for systematic comparative study of extraction mechanism, and comprehensively illustrated the roles of different force (hydrophobic interaction, π-π stacking interactions, hydrogen-bonding interaction, electrostatic interaction) for the first time. What’s more, the application guidelines for supporting materials, surfactants and sample matrix were also summarized. The extraction mechanism and platform established in the study render its future promising for foreseeable and efficient pretreatment under theoretical based experimental design for trace analytes from environmental, biological and clinical samples.

Employment of modified Fe3O4 nanoparticles using thermo‐sensitive polymer for extraction and pre‐concentration of cefexime in biological samples

“…Maximum magnetization intensities of the Fe 3 O 4 NPs and Fe 3 O 4 @PNVCL/AP NPs, based on VSM magnetization curves (Figure c), were 59.5 and 40.7 emu g −1 , respectively. This amount illustrates the suitably high magnetic power of the modified NPs, which makes them a proper choice for MSPE, so dispersed Fe 3 O 4 @PNVCL/AP NPs in solution can be extracted by an external magnet (Wang et al, ; Xiao et al, ). A clear decline in magnetic saturation value of the Fe 3 O 4 @PNVCL/AP NPs was recorded and this could be mostly because of the thick nonmagnetic polymer layer coating the Fe 3 O 4 NPs.…”

The Use of Modified Fe3O4 Particles to Recover Polyphenolic Compounds for the Valorisation of Olive Mill Wastewater from Slovenian Istria

“…Until now, research on the modification of magnetic particles for the enhanced extraction of polyphenols was performed by adsorbing ionic liquid or ionic surfactants on the surface of metal oxides [ 33 , 34 , 35 , 36 ]. The ionic liquid or surfactant’s hydrocarbon chains provide hydrophobic or π-π stacking interactions for hydrophobic analytes, while the polar groups adsorb ionic analytes via electrostatic interaction or a hydrogen-bonding interaction.…”