Platelet Transfusion and Death or Neurodevelopmental Impairment in Children Born Extremely Preterm
Patricia E. Davenport,
Thomas R. Wood,
Patrick J. Heagerty
et al.
Abstract:ImportanceInfants born extremely preterm receive transfusions at higher platelet count thresholds than older children and adults due to concerns for intracranial hemorrhage. A recent randomized trial comparing 2 platelet transfusion thresholds showed the higher threshold was associated with increased risk of long-term adverse neurodevelopmental outcomes.ObjectiveTo evaluate the association of platelet transfusion exposure with death and severe neurodevelopmental impairment (NDI) at 2 years’ corrected age in a … Show more
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