Platelet size

Bath, Philip M.W.; Butterworth, Richard

doi:10.1097/00001721-199603000-00011

Cited by 667 publications

(76 citation statements)

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“…It has been established that MPV was associated with higher platelet reactivity (Bath & Butterworth, 1996; van der Loo & Martin, 1999; Yetkin, 2008), which is involved in the pathophysiological mechanisms of depression (Musselman et al, 1996; Nemeroff & Musselman, 2000). …”

Section: Introductionmentioning

confidence: 99%

The association between mean platelet volume levels and poststroke depression

Qiu

Liu

et al. 2018

Brain and Behavior

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ObjectiveHigh levels of mean platelet volume (MPV) had been found in depression subjects. We sought to examine the relationship between MPV and poststroke depression (PSD).MethodsOne hundred and eighty‐five patients with acute ischemic stroke were enrolled in our study. Peripheral venous blood samples were drawn at admission and MPV levels were measured by the automated hematology analyzer. Patients with a HAMD‐17 score >7 were diagnosed as having PSD.ResultsWe found that 60 patients (32.4%) developed PSD, the MPV levels in PSD patients were significantly higher (9.3 ± 1.8 fl) compared to non‐PSD patients (8.5 ± 1.6 fl). High MPV levels (≥9.1 fl) were independently correlated with PSD (OR 2.762, 95% CI 1.138–6.702, p = 0.025).ConclusionsPatients with higher levels of MPV at admission were correlated with the development of PSD at 1 month after stroke and might be a predictor of its presence.

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Section: Introductionmentioning

confidence: 99%

The association between mean platelet volume levels and poststroke depression

Qiu

Liu

et al. 2018

Brain and Behavior

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“…It has been associated with thrombocyte volume, function, and activation. 6 MPV and platelet distribution width (PD�) are markers of platelet activation. 7�9 It is generally accepted that thrombocyte volume is determined during the produc� tion of thrombocytes from megakaryocytes.…”

Section: Introductionmentioning

confidence: 99%

Does varicocele correction lead to normalization of preoperatively elevated mean platelet volume levels?

Çoban

Ibrahim

Bıyık

et al. 2015

CUAJ

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Introduction: There are several studies on the relationship between increased mean platelet volume (MPV) and varicocele. �e inves� �e inves� tigated the relationship between preoperative and 6�month post� operative MPV values in patients whose varicocele was corrected with surgery. Methods: A total of 282 patients underwent surgery at our urology clinic between December 2011 and December 2013 for primary varicocele. �e retrospectively examined the records of 61 patients who came to the 6�month postoperative follow�up. The preop� erative varicocele diagnosis was made with physical examination findings and supported with colour Doppler ultrasonography. Results: The varicocele was grade I in 12 patients, grade II in 34 patients and grade III in 11 patients. �hen the preoperative and 6�month postoperative haemoglobin (Hb), MPV, mean corpuscular volume, platelet, and platelet distribution width (PD�) values were compared, there was a significant decrease in MPV (p = 0.019), and a significant increase in Hb (p < 0.001). A noticeable increase was also present in PD�, but it was not statistically significant (p = 0.058). Conclusion: �e found that MPV increased in patients with varic� ocele and tended to decrease again after the varicocele was sur� gically corrected. However, we feel larger prospective series are needed.

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“…Platelets, hemostasis and endothelial repair has a vital role, and also plays a significant role in the development of atherothrombosis [28]. Platelet volume is an indicator of platelet function and activation [29]. It has been reported that platelet count increases and MPV decreases in many inflammatory diseases [30,31].…”

Section: Discussionmentioning

confidence: 99%

Tooth fragments embedded in the lower lip following trauma

Benzer¹,

Duramaz²,

Önal³

et al. 2015

MMJ

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Objectives: Henoch-Schönlein purpura (HSP) or IgA vasculitis, is the most common form of childhood vasculitis. Mean platelet volume (MPV) is a parameter of a complete blood count that shows thrombocyte function and activation. This study evaluated the link between MPV and HSP. Patients and Methods:The data of 75 patients with a diagnosis of HSP were retrospectively evaluated. A control group was formed with 79 healthy children of similar gender and ages. results:The average ages were 6.8±3.02 years (44 males, 31 females) and 7.49±2.95 years (40 males, 39 females) for the patient and control groups respectively. Mean platelet volume was found to be significantly lower in the study group (p<0.0001). Patients' thrombocyte count were significantly higher (p<0.0001). Upon presentation 18 patients' faecal occult blood (FOB) test results were positive, and there was microscopic hematuria in 12 patients, MPV was found to be significantly lower in FOB positive patients (p=0.043).conclusion: Inflammation may affect MPV levels by increasing or decreasing. In our study, MPV measurements performed by a cheap and simple method, have been considered as a negative acute phase reactant. Decreased MPV measurements despite increased platelet count may be important in the prediction of hypercoagulopathy problems during the likely course of the disease and in close follow up for those with a predisposition. Ortalama trombosit hacmi çalışma grubunda anlamlı derecede düşük saptandı (p<0,0001). Hastaların trombosit sayısı anlamlı derecede yüksek bulundu (p<0,0001). Başvuru anında 18 hastada gizli gaite kan (GGK) testi pozitifti ve 12 hastada mikroskopik hematüri mevcuttu, GGK pozitif olan hastalarda OTH anlamlı düşük bulundu (p=0,043). sonuç: İnflamasyon, OTH düzeyini artma/azalma şeklinde etkileyebilmektedir. Çalışmamızda ucuz ve basit bir yöntem olan OTH ölçümleri negatif akut faz reaktanı olarak değerlendirilmiştir. Henoch-Schönlein purpuralı çocuklarda, artmış trombosit sayısına karşın, azalmış OTH ölçümlerinin, yatkınlığı olanlarda, hastalık seyrindeki olası hiperkoagülopati problemlerinin önceden belirlenmesinde ve yakın takipte önemli olabileceği kanısına varılmıştır.

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Platelet size

Cited by 667 publications

References 0 publications

The association between mean platelet volume levels and poststroke depression

The association between mean platelet volume levels and poststroke depression

Does varicocele correction lead to normalization of preoperatively elevated mean platelet volume levels?

Tooth fragments embedded in the lower lip following trauma

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