Platelet-rich plasma in surgical practice: a review

Abstract

The use of platelet-rich plasma (PRP) in clinical settings is a current issue in various fields of medicine. There is no unified and structured approach to PRP preparation and application stages. This review examines the literature data on the use of PRP in surgical practice. Data were analyzed using scientific sources from scientific citation platforms, such as RSCI, PubMed, Scopus, and Web of Science. This review describes the most commonly used methods and techniques for preparing PRP in laboratory and experimental conditions. Using data from clinical and experimental studies, the possibility and effectiveness of using PRP in routine and experimental surgical practice were analyzed. PRP has relatively wide range of applications in various areas of clinical medicine; however, its use in pediatric surgical practice requires further study, including the development of indications and contraindications.